ReviewTherapeutic advances in endocrinology and metabolism2017
Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature.
Review in Therapeutic advances in endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 64 citations in OpenAlex.
- Acute Pancreatitis Secondary to Hyperlipidemia After Exposure to Biktarvy and Alcohol in a HIV-Positive Patient:A Case Report.International medical case reports journal · 2026Article
- Acute pancreatitis: Translating early mechanisms to bedside management.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Review
- Ultra-early indicators of acute hypertriglyceridemic pancreatitis may influence treatment decision-making.Scientific reports · 2025Article
- Congenital Hyperlipidemia in Infants for Congenital Cardiac Surgery.JACC. Case reports · 2024Article
- Complicated Treatment Course of Severe Asymptomatic Hypertriglyceridemia: A Case Report and Literature Review.The American journal of case reports · 2024Review
- Plasmapheresis vs Conventional Insulin Therapy in Hypertriglyceridemia-Induced Acute Pancreatitis.Cureus · 2023Article
- Plasmapheresis can correct refractoriness of insulin on triglyceride metabolism - A case report of hypertriglyceridemia-induced acute pancreatitis.Archive of clinical cases · 2023Article
- Recurrent Hypertriglyceridemia-Induced Pancreatitis due to Multifactorial Chylomicronemia Syndrome in a Patient With Ketosis-Prone Diabetes Mellitus.Clinical medicine insights. Case reports · 2022Article
- Plasmapheresis in hypertriglyceridemia-induced acute pancreatitis.Proceedings (Baylor University. Medical Center) · 2022Article
- Severe acquired hypertriglyceridemia following COVID-19.BMJ case reports · 2021Article
- Therapeutic Plasmapheresis: A Treatment Modality in Severe Hypertriglyceridemia in Adolescence.Cureus · 2021Article
- Hypertriglyceridemia-Induced Pancreatitis With Rapid Response to Insulin Therapy.Journal of medical cases · 2021Article
- Hypertriglyceridemia and massive rhabdomyolysis in a patient with disseminated legionella.Respiratory medicine case reports · 2021Article
- Hypertriglyceridemia-associated acute pancreatitis: Response to continuous insulin infusion.PloS one · 2021Article
- Plasmapheresis Treatment of Hypertriglyceridemia-Induced Acute Pancreatitis: A Case Report.Cureus · 2020Article
- Effects of different triglyceride-lowering therapies in patients with hypertriglyceridemia-induced acute pancreatitis.Experimental and therapeutic medicine · 2020Article
- Hypertriglyceridemia and Atherosclerosis: Using Human Research to Guide Mechanistic Studies in Animal Models.Frontiers in endocrinology · 2020Review
- Idiopathic acute pancreatitis: a review on etiology and diagnostic work-up.Clinical journal of gastroenterology · 2019Review
- Double filtration plasmapheresis in treatment of acute pancreatitis associated with severe hypertriglyceridemia: Three case reports.Medicine · 2018Article
- Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience.Therapeutic advances in endocrinology and metabolism · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere hypertriglyceridemia (HTG) is the third leading cause of acute pancreatitis (AP) in the United States. The current standard of care includes management of HTG using pharmacological therapy. More recently, plasmapheresis has been proposed as a therapeutic tool for decreasing triglyceride (TG) levels, especially in critically ill patients. Few studies are available to ascertain overall benefits of plasmapheresis over traditional management.
objectiveTo analyze the outcomes of patients treated with plasmapheresis for severe HTG-associated pancreatitis.
methodsWe conducted a retrospective chart review of three patients with severe HTG- associated (TGs greater than 1000 mg/dl; 11.29 mmol/l) AP at the Methodist University Hospital. All the patients underwent plasmapheresis as part of their treatment.
resultsThe average TG level before plasmapheresis was 3532 mg/dl (range: 2524-4562 mg/dl; 39.9 mmol/l; range: 28.5-51.6 mmol/l). All patients made a full recovery, with a significant improvement in TG levels after plasmapheresis. The mean number of sessions was 1.3 (range 1-2), and mean TG level after plasmapheresis was 1051 mg/dl (range: 509-1771 mg/dl; 11.9 mmol/l; range: 5.8-20 mmol/l). After the first session, the average reduction of TG level was 2481 mg/dl (range 753-3750 mg/dl; 28 mmol/l; range: 8.5-42.4 mmol/l) or approximately 70%. None of the patients developed complications related to plasmapheresis.
conclusionsPlasmapheresis can be an effective and rapid treatment option in patients with severe HTG and complications. However, further research, including randomized controlled studies, is necessary.
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