Evidence map›Paper›PMID 28507675›Full record

ArticleChemical science2017

Psychosine variants as antigens for natural killer T cells.

S Deng, L Kain, C S Pereira, S Mata, M F Macedo, A Bendelac, L Teyton, P B Savage

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. NKT Cells Contribute to the Control of Microbial Infections.Frontiers in cellular and infection microbiology · 2021
    Review
  4. Article
  5. Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

S DengDepartment of Chemistry and Biochemistry , Brigham Young University , Provo , UT84602 , USA . Email: paul_savage@byu.edu.
L KainDepartment of Immunology , The Scripps Research Institute , La Jolla , CA 92037 , USA.
C S PereiraInstituto de Investigação e Inovação em Saúde , Universidade do Porto , Portugal.
S MataDepartment of Chemistry and Biochemistry , Brigham Young University , Provo , UT84602 , USA . Email: paul_savage@byu.edu.
M F MacedoInstituto de Investigação e Inovação em Saúde , Universidade do Porto , Portugal.ORCID 0000-0002-2252-6105
A BendelacCommittee on Immunology and Department of Pathology , Howard Hughes Medical Institute , University of Chicago , Chicago , IL 60637 , USA.
L TeytonDepartment of Immunology , The Scripps Research Institute , La Jolla , CA 92037 , USA.
P B SavageDepartment of Chemistry and Biochemistry , Brigham Young University , Provo , UT84602 , USA . Email: paul_savage@byu.edu.ORCID 0000-0002-4642-6109
Brigham Young University · USScripps Research Institute · USUniversidade do Porto · PTHoward Hughes Medical Institute · US

Funding

Molecular Pharmacology of NKT Cell AgonistsR01AI102892 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI TEYTON, LUC · 2013 to 2017
$3.6M
NIAID NIH HHS R01 AI102892
6 · The paper itself

Abstract

Natural killer T (NKT) cells play a central role in the interface between innate and adaptive immunity, and alpha-galactosylceramide was recently shown to be an endogenous antigen for these cells. The source of alpha-galactosylceramide has not yet been determined; however,

Identifiers

PMID28507675
PMCPMC5408565
OpenAlexW2560109412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.