Evidence map›Paper›PMID 28507674›Full record

ArticleChemical science2017

Highly specific C-C bond cleavage induced FRET fluorescence for

Hua Li, Deliang Zhang, Mengna Gao, Lumei Huang, Longguang Tang, Zijing Li, Xiaoyuan Chen, Xianzhong Zhang

Abstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. The Importance of Mechanical Forces forFrontiers in physiology · 2020
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. AnChemical science · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hua LiCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.
Deliang ZhangCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.
Mengna GaoCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.
Lumei HuangCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.
Longguang TangCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.
Zijing LiCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.
Xiaoyuan ChenLaboratory of Molecular Imaging and Nanomedicine (LOMIN) , National Institute of Biomedical Imaging and Bioengineering (NIBIB) , National Institutes of Health (USA) , Bethesda , Maryland 20892 , USA.ORCID 0000-0002-9622-0870
Xianzhong ZhangCenter for Molecular Imaging and Translational Medicine , State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , School of Public Health , Xiamen University , 361102 Xiamen , Fujian , China . Email: zhangxzh@xmu.edu.cn ; Email: zijing.li@xmu.edu.cn.ORCID 0000-0001-8591-8301

Funding

Laboratory of Molecular Imaging and NanomedicineZIAEB000073 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI CHEN, XIAOYUAN · 2010 to 2020
$32.8M
6 · The paper itself

Abstract

A novel Förster resonance energy transfer (FRET) fluorescence "off-on" system based on the highly specific, sensitive and effective C-C bond cleavage of certain dihydropyridine derivatives was reported for real-time quantitative imaging of nitric oxide (NO). 1,4-Dihydropyridine was synthesized as a novel linker which could connect customized fluorophores and their corresponding quenchers. The specific and quantitative response to NO is confirmed using fluorescence spectrometry with the classical example of fluorescein isothiocyanate (FITC) and [4'-(

Identifiers

PMID28507674
PMCPMC5407267

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.