ArticleOpen access Macedonian journal of medical sciences2017
Association between ABO and Rh Blood Groups and Risk of Preeclampsia: A Case-Control Study from Iran.
Article in Open access Macedonian journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Association Between ABO Blood Group and Preeclampsia: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
- [Relationship Between ABO Blood Group and Pregnancy Complications].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Review
- Relationship between ABO blood groups and gestational hypertensive disorders: A protocol for systematic review and meta-analysis.Medicine · 2021Article
- Placental protein 13: An important biological protein in preeclampsia.Journal of circulating biomarkersReview
- Association between maternal ABO blood group and preeclampsia: a prospective cohort study.Therapeutic advances in reproductive healthArticle
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2 authors.
Funding
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Abstract
aimPreeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality. There is a genetic component in the development of PE with estimated heritability around 0.47. Several studies have investigated the association between maternal ABO blood groups (OMIM 110300) and risk of PE, with contradictory results have emerged. Considering that there is no study in this filed from Iranian population, the present case-control study was carried out at Shiraz (south-west Iran). MATERIAL AND
methodsIn this study 331 women; 121 pregnant with PE and 210 normotensive pregnant women were included. Using blood group O (for ABO blood groups) or Rh+ (for Rh blood groups) as a reference, odds ratios (ORs) and its 95% confidence intervals (95% CI) of PE risk were estimated from logistic regression analysis.
resultsAlthough the A (OR = 0.67, 95% CI = 0.39-1.17, P = 0.165), B (OR = 0.86, 95% CI = 0.48-1.53, P = 0.615) and AB (OR = 1.14, 95% CI = 0.37-3.45, P = 0.812) phenotypes showed lower risks compared with the O blood group, statistical analysis indicated that there was no significant association between ABO phenotypes and risk of PE. The frequency of Rh- phenotype was higher among PE patients compared with the control group. However, the association was not significant (OR = 1.79, 95% CI = 0.69-4.65, P = 0.229). Adjusted ORs for age of participants and parity did not change the above-mentioned associations.
conclusionOur present findings indicate that there is no association between ABO and Rh blood groups and risk of PE in Iranian population.
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