Evidence map›Paper›PMID 28507623›Full record

ArticleOpen access Macedonian journal of medical sciences2017

Association between ABO and Rh Blood Groups and Risk of Preeclampsia: A Case-Control Study from Iran.

Firoozeh Aghasadeghi, Mostafa Saadat

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Article in Open access Macedonian journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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5citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. [Relationship Between ABO Blood Group and Pregnancy Complications].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Firoozeh AghasadeghiSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mostafa SaadatDepartment of Biology, College of Sciences, Shiraz University, Shiraz 71467-13565, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimPreeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality. There is a genetic component in the development of PE with estimated heritability around 0.47. Several studies have investigated the association between maternal ABO blood groups (OMIM 110300) and risk of PE, with contradictory results have emerged. Considering that there is no study in this filed from Iranian population, the present case-control study was carried out at Shiraz (south-west Iran). MATERIAL AND

methodsIn this study 331 women; 121 pregnant with PE and 210 normotensive pregnant women were included. Using blood group O (for ABO blood groups) or Rh+ (for Rh blood groups) as a reference, odds ratios (ORs) and its 95% confidence intervals (95% CI) of PE risk were estimated from logistic regression analysis.

resultsAlthough the A (OR = 0.67, 95% CI = 0.39-1.17, P = 0.165), B (OR = 0.86, 95% CI = 0.48-1.53, P = 0.615) and AB (OR = 1.14, 95% CI = 0.37-3.45, P = 0.812) phenotypes showed lower risks compared with the O blood group, statistical analysis indicated that there was no significant association between ABO phenotypes and risk of PE. The frequency of Rh- phenotype was higher among PE patients compared with the control group. However, the association was not significant (OR = 1.79, 95% CI = 0.69-4.65, P = 0.229). Adjusted ORs for age of participants and parity did not change the above-mentioned associations.

conclusionOur present findings indicate that there is no association between ABO and Rh blood groups and risk of PE in Iranian population.

Indexed as

ABOBlood groupPreeclampsiaRh

Identifiers

PMID28507623
PMCPMC5420769

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