Evidence map›Paper›PMID 28507582›Full record

ArticleArchives of medical science : AMS2017

Decreased activity of butyrylcholinesterase in blood plasma of patients with chronic obstructive pulmonary disease.

Paulina Sicinska, Bozena Bukowska, Aneta Pajak, Aneta Koceva-Chyla, Tadeusz Pietras, Piotr Nizinkowski, Paweł Gorski, Maria Koter-Michalak

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. The physiological effects of APOE genotype in healthy young/middle-aged individuals.Biological reviews of the Cambridge Philosophical Society · 2026
    Article
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. An investigation of the relation between catalaseArchives of medical science : AMS · 2021
    Article
  9. Archives of medical science : AMS · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Paulina SicinskaDepartment of Environmental Pollution Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Bozena BukowskaDepartment of Environmental Pollution Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Aneta PajakDepartment of Pneumology and Allergology, Norbert Barlicki Memorial University Hospital, Medical University of Lodz, Lodz, Poland.
Aneta Koceva-ChylaDepartment of Thermobiology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Tadeusz PietrasDepartment of Pneumology and Allergology, Norbert Barlicki Memorial University Hospital, Medical University of Lodz, Lodz, Poland.
Piotr NizinkowskiDepartment of Environmental Pollution Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Paweł GorskiDepartment of Pneumology and Allergology, Norbert Barlicki Memorial University Hospital, Medical University of Lodz, Lodz, Poland.
Maria Koter-MichalakDepartment of Environmental Pollution Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
University of Łódź · PLMedical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionButyrylcholinesterase (BChE) is involved in the metabolism of endogenous lipids and xenobiotics, such as esters of carboxylic or phosphoric acids. Butyrylcholinesterase activity is associated with both inflammation and oxidative stress. Changes in the activity of this enzyme have been observed in various diseases such as liver cirrhosis, diabetes, neurodegenerative disease and others. MATERIAL AND

methodsThe study involved 30 patients with chronic obstructive pulmonary disease (COPD) and 18 healthy subjects. The COPD patients were divided according to the severity of the disease by applying the classification of COPD based on GOLD standards for forced expiratory volume in 1 s (FEV

resultsA significant (

conclusionsThe study shows for the first time that activity of BChE in the blood plasma of patients diagnosed with chronic obstructive pulmonary disease is considerably reduced compared with healthy subjects. These changes were accompanied by a decrease of TAC and an increase of lipid peroxidation, which suggests that they may be related to the oxidative stress induced by COPD disease.

Indexed as

butyrylcholinesterasechronic obstructive pulmonary diseaselipid peroxidationoxidative stresspulmonary diseasetotal antioxidant capacity

Identifiers

PMID28507582
PMCPMC5420625
OpenAlexW2499998986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.