Evidence map›Paper›PMID 28507531›Full record

ArticleFrontiers in neurology2017

Noradrenergic Activation of Hypoglossal Nucleus Modulates the Central Regulation of Genioglossus in Chronic Intermittent Hypoxic Rats.

Xinshi Nie, Ling Zhou, Aidi Wang, Hongyu Jin, Zheng Qin, Jian Pang, Wei Wang, Jian Kang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinshi NieInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.
Ling ZhouInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.
Aidi WangInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.
Hongyu JinInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.
Zheng QinInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.
Jian PangThe 463rd Hospital of the Chinese PLA, Shenyang, China.
Wei WangInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.
Jian KangInstitute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromuscular compensation of the genioglossus muscle can be induced by chronic intermittent hypoxia (CIH) in obstructive sleep apnea to maintain upper airway stability. Noradrenergic activation of hypoglossal nucleus plays a critical role in the central control of the genioglossus. However, it remains unknown whether norepinephrine takes part in the central regulation of the genioglossus during CIH. Adult male Wistar rats (

Indexed as

central regulationgenioglossushypoglossal nucleusnorepinephrineobstructive sleep apneatranscranial magnetic stimulationα1-adrenergic antagonist

Identifiers

PMID28507531
PMCPMC5410562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.