Evidence map›Paper›PMID 28507504›Full record

ArticleFrontiers in neuroscience2017

Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression.

Bin Wang, Ying Wang, Qiong Wu, Hong-Ping Huang, Shao Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Antidepressant-like Effects ofPlants (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Article
  7. Neuroprotective actions of norepinephrine in neurological diseases.Pflugers Archiv : European journal of physiology · 2024
    Review
  8. Limited bedding and nesting increases ethanol drinking in female rats.Pharmacology, biochemistry, and behavior · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. PET imaging of animal models with depressive-like phenotypes.European journal of nuclear medicine and molecular imaging · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Genetic Polymorphism of rs13306146 AffectsFrontiers in genetics · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bin WangLiaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical UniversityDalian, China.
Ying WangLiaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical UniversityDalian, China.
Qiong WuLiaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical UniversityDalian, China.
Hong-Ping HuangDepartment of Physiology and Neurobiology, Wannan Medical CollegeWuhu, China.
Shao LiLiaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical UniversityDalian, China.
Dalian Medical University · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic stressors can often lead to the development of psychological disorders, such as depression and anxiety. The locus coeruleus (LC) is a stress sensitive brain region located in the pons, with noradrenergic neurons that project to the hypothalamus, especially the paraventricular nucleus (PVN) of the hypothalamus. The purpose of this paper is to better understand how alpha 2A-adrenoceptors (α

Indexed as

depressionhypothalamuslocus coeruleusnorepinephrineα2A-ardrenergic receptor

Identifiers

PMID28507504
PMCPMC5410613
OpenAlexW2610459568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.