Evidence map›Paper›PMID 28507489›Full record

ArticlePostepy dermatologii i alergologii2017

Evaluation of the serum zinc level in patients with vitiligo.

Majid Rostami Mogaddam, Nastaran Safavi Ardabili, Nasrollah Maleki, Mir Mehdi Chinifroush, Elham Maleki Fard

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Serum Copper and Zinc Levels Among Iranian Vitiligo Patients.Dermatology practical & conceptual · 2022
    Article
  4. Article
  5. Serum Zinc and Inflammatory Cytokines in Vitiligo.The Journal of clinical and aesthetic dermatology · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Majid Rostami MogaddamDepartment of Dermatology, Imam Khomeini Hospital, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Nastaran Safavi ArdabiliDepartment of Midwifery, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
Nasrollah MalekiThe Persian Gulf Tropical Medicine Research Center, Department of Internal Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
Mir Mehdi ChinifroushDepartment of Pathology, Imam Khomeini Hospital, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Elham Maleki FardDepartment of Dermatology, Imam Khomeini Hospital, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Imam Khomeini Hospital · IRArdabil University of Medical Sciences · IRBushehr University of Medical Sciences · IRIslamic Azad University Ardabil · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVitiligo is an acquired, idiopathic disorder characterized by circumscribed depigmented macules and patches, which affects approximately 0.1-2% of the general population worldwide. Zinc is an essential trace element that is necessary for growth and development at all stages of life. Some studies have reported an association between serum zinc levels and vitiligo.

aimTo measure the serum zinc level in patients with vitiligo compared to healthy subjects. MATERIAL AND

methodsOne hundred patients with vitiligo and 100 healthy controls were referred to our clinic. The two groups were matched for age and sex. Atomic absorption spectrophotometry was used to measure serum zinc levels. The statistical analysis was performed using SPSS software.

resultsThe mean serum level of zinc in vitiligo patients and controls was 80.11 ±17.10 μg/dl and 96.10 ±16.16 μg/dl, respectively. The serum zinc level in patients with vitiligo was significantly lower than in healthy controls (

conclusionsThe results of our study revealed a significant association between vitiligo and serum zinc levels. A relative decrease in the serum zinc level in vitiligo patients can highlight the role of zinc in the pathogenesis of vitiligo, and large-scale studies need to be conducted to confirm these findings and assess the effect of oral zinc supplements in patients with low zinc levels.

Indexed as

serum levelvitiligozinc

Identifiers

PMID28507489
PMCPMC5420602
OpenAlexW2608796960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.