Evidence map›Paper›PMID 28507300›Full record

ArticleScientific reports2017

Minimum toe clearance: probing the neural control of locomotion.

Tim Killeen, Christopher S Easthope, László Demkó, Linard Filli, Lilla Lőrincz, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02165787 (Investigation of Gait Parameters in Health and Neurological Disease Under Varying Locomotor Conditions), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02165787 completednot on this map

Investigation of Gait Parameters in Health and Neurological Disease Under Varying Locomotor Conditions

TypeobservationalSponsorUniversity of ZurichRan2014 to 2019Enrolled208ConditionsGait Analysis in Neurological Disorders
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 57 citations in OpenAlex.

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  8. Females Present Reduced Minimum Toe Clearance During Walking As Compared to Males in Active Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tim KilleenSpinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland. tim.killeen@balgrist.ch.ORCID 0000-0001-8246-4957
Christopher S EasthopeSpinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland.
László DemkóSpinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland.
Linard FilliDepartment of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.
Lilla LőrinczDepartment of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.
Michael LinnebankDepartment of Neurology, Helios-Klinik Hagen-Ambrock, Ambrocker Weg 60, 58091, Hagen, Germany.
Armin CurtSpinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland.
Björn ZörnerSpinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland.
Marc BolligerSpinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland.
Universitätsklinik Balgrist · CHUniversity Hospital of Zurich · CHHelios Klinik Hagen Ambrock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance but how these factors interact to influence MTC control is not fully understood. We measured MTC in 121 healthy individuals aged 20-80 under four treadmill walking conditions; normal walking, lower visual field restriction and two Stroop colour/word naming tasks of two difficulty levels. Competition for cognitive and attentional resources from the Stroop task resulted in significantly lower mean MTC in older adults, with the difficult Stroop task associated with a higher frequency of extremely low MTC values and subsequently an increased modelled probability of tripping in this group. While older adults responded to visual restriction by markedly skewing MTC distributions towards higher values, this condition was also associated with frequent, extremely low MTC values. We reveal task-specific, age-dependent patterns of MTC control in healthy adults. Age-related differences are most pronounced during heavy, distracting cognitive load. Analysis of critically-low MTC values during dual-task walking may have utility in the evaluation of locomotor control and fall risk in older adults and patients with motor control deficits.

Indexed as

GaitLocomotionPsychomotor PerformanceAdultAgedAged, 80 and overExercise TestFemaleHumansMaleMiddle AgedModels, TheoreticalYoung Adult

Identifiers

PMID28507300
PMCPMC5432520
OpenAlexW2613036214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.