ReviewCold Spring Harbor perspectives in medicine2018
Performance Fatigability: Mechanisms and Task Specificity.
Review in Cold Spring Harbor perspectives in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03644329 (Effect of Resistance Training Variable Manipulation), which is not on this map. Cited by 80 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Resistance Training Variable Manipulation (Intensity and Volume) on Body Composition, Fatigability and Functional Capacity in Postmenopausal Breast Cancer Survivors.
Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Advanced Resistance Training Prescription Methods on Strength, Power, Hypertrophy, and Performance Adaptations in Healthy Adults: A Systematic Review and Bayesian Network Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Exploring the interplay between quantitative muscle strength, functional performance, and patient-reported outcomes in amyotrophic lateral sclerosis: a cross-sectional pilot study.Scientific reports · 2026Trial
- Effects of a symptom-titrated exercise program on fatigue and quality of life in people with post-COVID condition - a randomized controlled trial.Scientific reports · 2024Trial
- Low-load Resistance Exercise with Perceptually Primed Practical Blood Flow Restriction Induces Similar Motor Performance Fatigue, Physiological Changes, and Perceptual Responses Compared to Traditional Blood Flow Restriction in Males and Females.Journal of sports science & medicine · 2024Trial
- Trial
- Investigating the Effects of Mental Fatigue on Resistance Exercise Performance.International journal of environmental research and public health · 2021Trial
- Delaying task failure in high-intensity exercise: a Pi-afferent-effort framework for targeted sports nutrition.Journal of the International Society of Sports Nutrition · 2026Review
- Passive thigh heating increases peak torque but does not attenuate declines in force production during repeated isokinetic knee extensor exercise in older adults.Physiological reports · 2026Article
- Sex differences in climbing endurance emerge from combined physiological adaptation and neural strategies.European journal of applied physiology · 2026Article
- Real-Time Physiological Fatigue Prediction for Human-Robot Collaborative Manufacturing Using Wearable Sensor Fusion and Hybrid Deep Learning: An In Silico Digital Twin Study.Sensors (Basel, Switzerland) · 2026Article
- Economy benefits of running in advanced footwear technology shoes remain with plantarflexion fatigue.European journal of applied physiology · 2026Article
- Indicators of Neuromuscular, Metabolic and Perceptual Fatigue Following a 5 km Run.Sports (Basel, Switzerland) · 2026Article
- Can Changes in Sit-To-Stand Performance Throughout A 30-S Time Interval Be Used as A Marker of Performance Fatigability in Middle-Aged To Older Adults?Journal of sports science & medicine · 2026Article
- Stroke Increases Neuromuscular Fatigability in Females but not Males during Isometric Exercise.Medicine and science in sports and exercise · 2026Article
- Effect of hypoxia on muscle activation at equivalent absolute and relative intensity during incremental and constant load exercise to task failure.Experimental physiology · 2026Article
- Wrist muscle performance in students with chronic nonspecific neck pain: an isokinetic assessment.BMC musculoskeletal disorders · 2026Observational
- Concurrent HIIT and Resistance Training for Musculoskeletal Function: A Systematic Review of Neuromuscular, Morphological, and Performance Adaptations.Life (Basel, Switzerland) · 2026Review
- Relative Handgrip Strength as the Primary Determinant of Fatigue Resistance in Young Adults.International journal of exercise science · 2026Article
- Article
- Motor performance and aging in males and females.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Performance fatigability is characterized as an acute decline in motor performance caused by an exercise-induced reduction in force or power of the involved muscles. Multiple mechanisms contribute to performance fatigability and originate from neural and muscular processes, with the task demands dictating the mechanisms. This review highlights that (1) inadequate activation of the motoneuron pool can contribute to performance fatigability, and (2) the demands of the task and the physiological characteristics of the population assessed, dictate fatigability and the involved mechanisms. Examples of task and population differences in fatigability highlighted in this review include contraction intensity and velocity, stability and support provided to the fatiguing limb, sex differences, and aging. A future challenge is to define specific mechanisms of fatigability and to translate these findings to real-world performance and exercise training in healthy and clinical populations across the life span.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.