Evidence map›Paper›PMID 28507103›Full record

ArticleCancer research2017

Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.

Francesco Piacente, Irene Caffa, Silvia Ravera, Giovanna Sociali, Mario Passalacqua, Valerio G Vellone, Pamela Becherini, Daniele Reverberi, Fiammetta Monacelli, Alberto Ballestrero and 7 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The role of NADnpj metabolic health and disease · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Mechanisms of resistance to NAMPT inhibitors in cancer.Cancer drug resistance (Alhambra, Calif.) · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Trigonelline is an NADNature metabolism · 2024
    Article
  17. Article
  18. Inhibitors of NADInternational journal of molecular sciences · 2024
    Review
  19. Mechanisms of the NADFrontiers in cell and developmental biology · 2024
    Review
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Francesco PiacenteDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Irene CaffaDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Silvia RaveraDepartment of Pharmacy, Biochemistry Lab, Genoa, Italy.
Giovanna SocialiDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Mario PassalacquaDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Valerio G VelloneDepartment of Integrated, Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy.
Pamela BecheriniDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Daniele ReverberiOspedale Policlinico San Martino, I.R.C.C.S. per l'Oncologia, Genoa, Italy.
Fiammetta MonacelliDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Alberto BallestreroDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Patrizio OdettiDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Antonia CagnettaDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Michele CeaDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Aimable NahimanaService and Central Laboratory of Hematology, University Hospital of Lausanne, Lausanne, Switzerland.
Michel DuchosalService and Central Laboratory of Hematology, University Hospital of Lausanne, Lausanne, Switzerland.
Santina BruzzoneDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Alessio NencioniDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy. alessio.nencioni@unige.it.
University of Genoa · ITOspedale Policlinico San Martino · ITUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, substantial efforts have been made to identify NAD

Indexed as

DNA RepairAnimalsCell Line, TumorCytokinesEnzyme InhibitorsFemaleGene AmplificationHEK293 CellsHeterograftsHumansMiceMice, Inbred BALB CMice, NudeNicotinamide PhosphoribosyltransferaseOvarian NeoplasmsXenograft Model Antitumor AssaysCytokinesEnzyme InhibitorsNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, human

Identifiers

PMID28507103
OpenAlexW2616286706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.