ArticleThe EMBO journal2017
Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.
Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 175 citations in OpenAlex.
- Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models.HemaSphere · 2025Article
- Rejuvenation of the reconstitution potential and reversal of myeloid bias of aged HSCs upon pH treatment.Aging cell · 2024Article
- Epidermal growth factor augments the self-renewal capacity of aged hematopoietic stem cells.iScience · 2024Article
- The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression.Blood advances · 2023Article
- Metabolic reprogramming in inflammaging and aging in T cells.Life metabolism · 2023Review
- Article
- Targeting the stem cell niche micro-environment as therapeutic strategies in aging.Frontiers in cell and developmental biology · 2023Review
- Aging, Causes, and Rejuvenation of Hematopoietic Stem Cells.Advances in experimental medicine and biology · 2023Article
- Article
- Article
- Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.The Journal of experimental medicine · 2021Article
- Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches.Journal of hematology & oncology · 2020Review
- Endothelial mTOR maintains hematopoiesis during aging.The Journal of experimental medicine · 2020Article
- Hematopoiesis and Cardiovascular Disease.Circulation research · 2020Review
- Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer.BMC cancer · 2019Article
- Haematopoietic stem cell activity and interactions with the niche.Nature reviews. Molecular cell biology · 2019Review
- Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.JCI insight · 2019Article
- Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.The Journal of experimental medicine · 2019Article
- Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish.Blood advances · 2018Review
- A Glimpse into Uveitis in the Aging Eye: Pathophysiology, Clinical Presentation and Treatment Considerations.Drugs & aging · 2018Review
Corrections and comments
- Erratum for
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.