Evidence map›Paper›PMID 28507067›Full record

ArticleInfection and immunity2017

Global Transcriptional Response to Organic Hydroperoxide and the Role of OhrR in the Control of Virulence Traits in Chromobacterium violaceum.

Maristela Previato-Mello, Diogo de Abreu Meireles, Luis Eduardo Soares Netto, José Freire da Silva Neto

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. A cytochromeApplied and environmental microbiology · 2025
    Article
  2. Regulation of virulence inFrontiers in microbiology · 2024
    Review
  3. The Arsenal ofAntioxidants (Basel, Switzerland) · 2023
    Review
  4. Article
  5. Organic Hydroperoxide Induces Prodigiosin Biosynthesis inApplied and environmental microbiology · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Organic Hydroperoxide Resistance GeneApplied and environmental microbiology · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. MarR Family Transcription Factors fromMicrobiology and molecular biology reviews : MMBR · 2019
    Review
  15. Article
  16. Article
  17. Frontiers in microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Maristela Previato-MelloDepartamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Diogo de Abreu MeirelesDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, SP, Brazil.
Luis Eduardo Soares NettoDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, SP, Brazil.
José Freire da Silva NetoDepartamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil jfsneto@usp.br.ORCID http://orcid.org/0000-0002-7946-2747
Universidade de Ribeirão Preto · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major pathway for the detoxification of organic hydroperoxides, such as cumene hydroperoxide (CHP), involves the MarR family transcriptional regulator OhrR and the peroxidase OhrA. However, the effect of these peroxides on the global transcriptome and the contribution of the OhrA/OhrR system to bacterial virulence remain poorly explored. Here, we analyzed the transcriptome profiles of

Indexed as

Transcription, GeneticAnimalsBacterial LoadBacterial ProteinsBenzene DerivativesChitinasesChromobacteriumCollagenasesEscherichia coli ProteinsGene Expression ProfilingGene Expression Regulation, BacterialGram-Negative Bacterial InfectionsHemolysin ProteinsHumansHydrogen PeroxideLiverBacterial ProteinsBenzene DerivativesChitinasesCollagenasescumene hydroperoxidediguanylate cyclaseEscherichia coli ProteinsHemolysin ProteinsHydrogen PeroxideOxygenasesPeroxidasesperoxide repressor proteinsPhosphorus-Oxygen LyasesRepressor ProteinsTranscription FactorsVirulence Factorsbacterial virulenceCHP stimuloncumene hydroperoxidediguanylate cyclaseMarR familyOhrA/OhrR systemorganic hydroperoxidesoxidative stresstranscription factors

Identifiers

PMID28507067
PMCPMC5520425
OpenAlexW2615980615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.