Evidence map›Paper›PMID 28507058›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Hepatocyte Nuclear Factor-1

Karam Aboudehen, Lama Noureddine, Patricia Cobo-Stark, Svetlana Avdulov, Shayan Farahani, Micah D Gearhart, Daniel G Bichet, Marco Pontoglio, Vishal Patel, Peter Igarashi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Clinical kidney journal · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Role of FXR in Renal Physiology and Kidney Diseases.International journal of molecular sciences · 2023
    Review
  10. Aquaporins in Urinary System.Advances in experimental medicine and biology · 2023
    Article
  11. Article
  12. Review
  13. Emerging roles for AQP in mammalian extracellular vesicles.Biochimica et biophysica acta. Biomembranes · 2022
    Review
  14. Article
  15. A methionine-Mettl3-NCell metabolism · 2021
    Article
  16. Deletion ofAmerican journal of physiology. Renal physiology · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Karam AboudehenDepartments of Medicine and.
Lama NoureddineDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Patricia Cobo-StarkDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Svetlana AvdulovDepartments of Medicine and.
Shayan FarahaniDepartments of Medicine and.
Micah D GearhartGenetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota.
Daniel G BichetDepartments of Medicine and.
Marco PontoglioDepartment of Development, Reproduction and Cancer, Institut Cochin, Institut National de la Santé et de la Recherche Médicale U1016/Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Université Paris-Descartes, Paris, France.
Vishal PatelDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Peter IgarashiDepartments of Medicine and Igarashi@umn.edu.
The University of Texas Southwestern Medical Center · USUniversité de Montréal · CAUniversité Paris Cité · FRUniversity of Iowa · USUniversity of Minnesota · US

Funding

UT Southwestern O'Brien Kidney Research Core CenterP30DK079328 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MOE, ORSON W · 2007 to 2021
$16.9M
REGULATION OF RENAL NA+/H+ EXCHANGER GENE EXPRESSIONR01DK042921 · NIDDK · YALE UNIVERSITY · PI IGARASHI, PETER · 1991 to 2025
$5.1M
RENAL CONTROL OF BODY COMPOSITION AND BLOOD PRESSURET32DK007257 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI BAUM, MICHEL GERARD, MOE, ORSON W · 1986 to 2021
$5.0M
Regulation of Kidney-Specific Gene ExpressionR37DK042921 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI IGARASHI, PETER · 2011 to 2020
$3.6M
The impact of RNA chemical modifications on polycystic kidney disease progressionR01DK102572 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI PATEL, VISHAL · 2015 to 2024
$3.5M
Role of microRNA in kidney development and pathogenesis of PKDK08DK084311 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI PATEL, VISHAL · 2009 to 2013
$728k
NIDDK NIH HHS K08 DK084311NIDDK NIH HHS P30 DK079328NIDDK NIH HHS R01 DK042921NIDDK NIH HHS R01 DK102572NIDDK NIH HHS R37 DK042921NIDDK NIH HHS T32 DK007257
6 · The paper itself

Abstract

The transcription factor hepatocyte nuclear factor-1

Indexed as

AnimalsCell LineFemaleGene Expression RegulationHepatocyte Nuclear Factor 1-betaKidney Tubules, CollectingMaleMice, TransgenicPolyuriaPromoter Regions, GeneticReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearUrineHepatocyte Nuclear Factor 1-betaHnf1b protein, mouseReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and Nuclearcollecting ductscystic kidneyosmolalitytranscription factorsureawater-electrolyte balance

Identifiers

PMID28507058
PMCPMC5619957
OpenAlexW2614359283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.