Evidence map›Paper›PMID 28506980›Full record

ArticleCirculation. Cardiovascular quality and outcomes2017

Sex Differences in Trajectories of Risk After Rehospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia.

Rachel P Dreyer, Kumar Dharmarajan, Angela F Hsieh, John Welsh, Li Qin, Harlan M Krumholz

Abstract readMulticenter Study
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Effect ofFrontiers in medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bending Primordial Trajectories Away From Heart Failure.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel P DreyerFrom the Center for Outcomes Research and Evaluation (CORE), Yale New Haven Health, CT (R.P.D., K.D., A.F.H., J.W., L.Q., H.M.K.); and Department of Emergency Medicine (R.P.D.), Section of Cardiovascular Medicine, Department of Internal Medicine (K.D., H.M.K.), Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine (H.M.K.), and Department of Health Policy and Management (H.M.K.), Yale School of Public Health, New Haven, CT. rachel.dreyer@yale.edu.
Kumar DharmarajanFrom the Center for Outcomes Research and Evaluation (CORE), Yale New Haven Health, CT (R.P.D., K.D., A.F.H., J.W., L.Q., H.M.K.); and Department of Emergency Medicine (R.P.D.), Section of Cardiovascular Medicine, Department of Internal Medicine (K.D., H.M.K.), Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine (H.M.K.), and Department of Health Policy and Management (H.M.K.), Yale School of Public Health, New Haven, CT.
Angela F HsiehFrom the Center for Outcomes Research and Evaluation (CORE), Yale New Haven Health, CT (R.P.D., K.D., A.F.H., J.W., L.Q., H.M.K.); and Department of Emergency Medicine (R.P.D.), Section of Cardiovascular Medicine, Department of Internal Medicine (K.D., H.M.K.), Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine (H.M.K.), and Department of Health Policy and Management (H.M.K.), Yale School of Public Health, New Haven, CT.
John WelshFrom the Center for Outcomes Research and Evaluation (CORE), Yale New Haven Health, CT (R.P.D., K.D., A.F.H., J.W., L.Q., H.M.K.); and Department of Emergency Medicine (R.P.D.), Section of Cardiovascular Medicine, Department of Internal Medicine (K.D., H.M.K.), Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine (H.M.K.), and Department of Health Policy and Management (H.M.K.), Yale School of Public Health, New Haven, CT.
Li QinFrom the Center for Outcomes Research and Evaluation (CORE), Yale New Haven Health, CT (R.P.D., K.D., A.F.H., J.W., L.Q., H.M.K.); and Department of Emergency Medicine (R.P.D.), Section of Cardiovascular Medicine, Department of Internal Medicine (K.D., H.M.K.), Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine (H.M.K.), and Department of Health Policy and Management (H.M.K.), Yale School of Public Health, New Haven, CT.
Harlan M KrumholzFrom the Center for Outcomes Research and Evaluation (CORE), Yale New Haven Health, CT (R.P.D., K.D., A.F.H., J.W., L.Q., H.M.K.); and Department of Emergency Medicine (R.P.D.), Section of Cardiovascular Medicine, Department of Internal Medicine (K.D., H.M.K.), Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine (H.M.K.), and Department of Health Policy and Management (H.M.K.), Yale School of Public Health, New Haven, CT.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Geriatric Conditions and Readmission after Acute Myocardial InfarctionK23AG048331 · NIA · YALE UNIVERSITY · PI DHARMARAJAN, KUMAR · 2014 to 2017
$692k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K23 AG048331NIA NIH HHS P30 AG021342
6 · The paper itself

Abstract

backgroundWomen have an increased risk of rehospitalization in the immediate postdischarge period; however, few studies have determined how readmission risk dynamically changes on a day-to-day basis over the full year after hospitalization by sex and how these differences compare with the risk for mortality. METHODS AND

resultsWe identified >3 000 000 hospitalizations of patients with a principal discharge diagnosis of heart failure, acute myocardial infarction, or pneumonia and estimated sex differences in the daily risk of rehospitalization/death 1 year after discharge from a population of Medicare fee-for-service beneficiaries aged 65 years and older. We calculated the (1) time required for adjusted rehospitalization/mortality risks to decline 50% from maximum values after discharge, (2) time required for the adjusted readmission risk to approach plateau periods of minimal day-to-day change, and (3) extent to which adjusted risks are greater among recently hospitalized patients versus Medicare patients. We identified 1 392 289, 530 771, and 1 125 231 hospitalizations for heart failure, acute myocardial infarction, and pneumonia, respectively. The adjusted daily risk of rehospitalization varied by admitting condition (hazard rate ratio for women versus men, 1.10 for acute myocardial infarction; hazard rate ratio, 1.04 for heart failure; and hazard rate ratio, 0.98 for pneumonia). However, for all conditions, the adjusted daily risk of death was higher among men versus women (hazard rate ratio women versus with men, <1). For both sexes, there was a similar timing of peak daily risk, half daily risk, and reaching plateau.

conclusionsAlthough the association of sex with daily risk of rehospitalization varies across conditions, women are at highest risk after discharge for acute myocardial infarction. Future studies should focus on understanding the determinants of sex differences in rehospitalization risk among conditions.

Indexed as

AgedAged, 80 and overFee-for-Service PlansFemaleHeart FailureHumansIncidenceMaleMedicareMyocardial InfarctionPatient ReadmissionPneumoniaRetrospective StudiesRisk AssessmentRisk FactorsSex Distributionheart failurehospitalizationmyocardial infarctionpneumoniawomen

Identifiers

PMID28506980
PMCPMC5650228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.