Evidence map›Paper›PMID 28506846›Full record

ArticleThe Journal of allergy and clinical immunology2018

Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells.

Véronique Schulten, Victoria Tripple, Grégory Seumois, Yu Qian, Richard H Scheuermann, Zheng Fu, Michela Locci, Sandy Rosales, Pandurangan Vijayanand, Alessandro Sette and 3 more

Abstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026
    Review
  3. Recent advances in allergen immunotherapy.Chinese medical journal · 2026
    Review
  4. Circulating TFH2 Cell Expansion and GZMKJournal of asthma and allergy · 2026
    Article
  5. IL-21 expression during sublingual immunotherapy for allergic rhinitis.American journal of clinical and experimental immunology · 2026
    Article
  6. [Chinese expert consensus on the evaluation of allergen-specific immunotherapy outcomes(Wuhan, 2025)].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Allergen Immunotherapy in Asthma.Pathogens (Basel, Switzerland) · 2021
    Review
  12. Review
  13. Reduced CCR6Frontiers in immunology · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Véronique SchultenLa Jolla Institute for Allergy & Immunology, La Jolla, Calif. Electronic address: Veronique@lji.org.
Victoria TrippleLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Grégory SeumoisLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Yu QianJ. Craig Venter Institute, La Jolla, Calif.
Richard H ScheuermannJ. Craig Venter Institute, La Jolla, Calif; Department of Pathology, University of California, San Diego, Calif.
Zheng FuLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Michela LocciLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Sandy RosalesLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Pandurangan VijayanandLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Alessandro SetteLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Rafeul AlamNational Jewish Health, Denver, Colo.
Shane CrottyLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
Bjoern PetersLa Jolla Institute for Allergy & Immunology, La Jolla, Calif.
La Jolla Institute for Immunology · USJ. Craig Venter Institute · USUniversity of Colorado Denver · US

Funding

Single-cell atlas of lung tissue-resident memory T cells reactive to upper and lower respiratory tract pathogensU19AI118626 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Alessandro Sette · 2015 to 2026
$36.7M
Understanding mechanisms in specific immunotherapy (SIT)U19AI100275 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SETTE, ALESSANDRO · 2012 to 2017
$8.1M
Airway Th2Th17 Cells in Refractory AsthmaR01HL126895 · NHLBI · NATIONAL JEWISH HEALTH · PI ALAM, RAFEUL · 2016 to 2019
$1.8M
Sprouty-2 Regulation of Signaling in AsthmaR01AI102943 · NIAID · NATIONAL JEWISH HEALTH · PI ALAM, RAFEUL · 2014 to 2017
$1.6M
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NHLBI NIH HHS R01 HL126895NIAID NIH HHS HHSN272200700048CNIAID NIH HHS R01 AI102943NIAID NIH HHS U19 AI100275NIAID NIH HHS U19 AI118626
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ImmunotherapyPhleumAdultAgedAllergensFemaleHumansHypersensitivityMaleMiddle AgedT-Lymphocytes, Helper-InducerAllergens

Identifiers

PMID28506846
PMCPMC5682232
OpenAlexW2613007683

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.