ArticleVirus research2017
Discovery of a novel canine respiratory coronavirus support genetic recombination among betacoronavirus1.
Article in Virus research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- A Review: Bovine Coronavirus Evolution, Molecular Epidemiology, and Genetic Variation.Viruses · 2026Review
- Farm animal coronaviruses: the solution is in vaccines.The veterinary quarterly · 2025Review
- Characteristics of an emerging canine respiratory coronavirus in China.The veterinary quarterly · 2025Article
- Development and validation of nanoplate-based RT-dPCR assay for canine respiratory coronavirus detection in various clinical samples.BMC veterinary research · 2025Article
- Detection of avian, murine, bovine, shrew, and bat coronaviruses in wild mammals from Mexico.Virology journal · 2025Article
- Discovery of a novel Betacoronavirus 1, cpCoV, in goats in China: The new risk of cross-species transmission.PLoS pathogens · 2025Article
- Circulation and Genetic Characterizations of Coronaviruses From Companion Animals in Chengdu, Southwest China: One-Year Postpandemic.Transboundary and emerging diseases · 2025Article
- Molecular detection of canine viral infectious diseases in China: an investigation from 2018 to 2024.Frontiers in veterinary science · 2025Article
- Epidemiologic investigation and genetic characterization of canine respiratory coronavirus in the Southeastern United States.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Article
- Incidence and Genetic Investigation of Avian Coronaviruses in Migratory Ducks From South Korea.Transboundary and emerging diseases · 2024Article
- Canine respiratory coronavirus in Thailand undergoes mutation and evidences a potential putative parent for genetic recombination.Microbiology spectrum · 2023Article
- Emerging SARS-CoV-2 variants of concern potentially expand host range to chickens: insights from AXL, NRP1 and ACE2 receptors.Virology journal · 2023Article
- Advances in Bovine Coronavirus Epidemiology.Viruses · 2022Review
- Molecular phylogeny of coronaviruses and host receptors among domestic and close-contact animals reveals subgenome-level conservation, crossover, and divergence.BMC veterinary research · 2022Article
- Diversity of Coronaviruses with Particular Attention to the Interspecies Transmission of SARS-CoV-2.Animals : an open access journal from MDPI · 2022Review
- Coronavirus Infections in Animals: Risks of Direct and Reverse Zoonoses.Herald of the Russian Academy of Sciences · 2022Article
- Review
- RETRACTED: Rapid Generation of Coronaviral Immunity Using Recombinant Peptide Modified Nanodiamonds.Pathogens (Basel, Switzerland) · 2021Article
- Animal Coronaviruses and SARS-COV-2 in Animals, What Do We Actually Know?Life (Basel, Switzerland) · 2021Review
- Coronaviruses in wild birds - A potential and suitable vector for global distribution.Veterinary medicine and science · 2021Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although canine respiratory coronavirus (CRCoV) is an important respiratory pathogen that is prevalent in many countries, only one complete genome sequence of CRCoV (South Korea strain K37) has been obtained to date. Genome-wide analyses and recombination have rarely been conducted, as small numbers of samples and limited genomic characterization have previously prevented further analyses. Herein, we report a unique CRCoV strain, denoted strain BJ232, derived from a CRCoV-positive dog with a mild respiratory infection. Phylogenetic analysis based on complete genome of all available coronaviruses consistently show that CRCoV BJ232 is most closely related to human coronavirus OC43 (HCoV-OC43) and BCoV, forming a separate clade that split off early from other Betacoronavirus 1. Based on the phylogenetic and SimPlot analysis we propose that CRCoV-K37 was derived from genetic recombination between CRCoV-BJ232 and BCoV. In detail, spike (S) gene of CRCoV-K37 clustered with CRCoV-BJ232. However orf1ab, membrane (M) and nucleocapsid (N) genes were more related to Bovine coronavirus (BCoV) than CRCoV-B232. Molecular epidemic analysis confirmed the prevalence of CRCoV-BJ232 lineage around the world for a long time. Recombinant events among Betacoronavirus 1 may have implications for CRCoV transmissibility. All these findings provide further information regarding the origin of CRCoV.
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