Observational studyClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2018
Healthcare personnel intestinal colonization with multidrug-resistant organisms.
Observational study in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01952158 (Point Prevalence Study of Multidrug-Resistant Organism Carriage by Healthcare Personnel), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Point Prevalence Study of Multidrug-Resistant Organism Carriage by Healthcare Personnel
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Occupational Infection Risk with Multidrug-Resistant Organisms in Health Personnel-A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- Effectiveness of healthcare worker screening in hospital outbreaks with gram-negative pathogens: a systematic review.Antimicrobial resistance and infection control · 2018Pooled it
- Elevated antibiotic resistance gene abundance of ICU healthcare workers, a multicentre, cross-sectional study.Critical care (London, England) · 2025Observational
- Detection and Antimicrobial Susceptibility of Carbapenem-Resistant Organisms Isolated in the Center of Care and Protection of Orphan Children, Vietnam.International journal of microbiology · 2025Article
- Evaluation of multidrug-resistant bacteria and their molecular mechanisms found in small animal veterinary practices in Portugal.Frontiers in cellular and infection microbiology · 2025Article
- Article
- Colonization with resistant bacteria in hospital employees: an epidemiological surveillance and typing study.Antimicrobial agents and chemotherapy · 2024Article
- High carriage rate of extended-spectrum β-lactamase Enterobacterales and diarrheagenic Escherichia coli in healthy donor screening for fecal microbiota transplantation.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- Source-tracking ESBL-producing bacteria at the maternity ward of Mulago hospital, Uganda.PloS one · 2023Article
- Article
- High prevalence of extended-spectrum beta-lactamase organisms and the COVID-19 pandemic impact on donor recruitment for fecal microbiota transplantation in Hong Kong.United European gastroenterology journal · 2021Article
- Antibiotic-Resistant Gram-negative Bacteria Carriage in Healthcare Workers Working in an Intensive Care Unit.Infection & chemotherapy · 2021Article
- Multidrug-resistant bacteria as intestinal colonizers and evolution of intestinal colonization in healthy university students in Portugal.Access microbiology · 2021Article
- Fecal Microbiota Transplantation: Screening and Selection to Choose the Optimal Donor.Journal of clinical medicine · 2020Review
- Colonization With Multidrug-Resistant Organisms Among Healthy Adults in the Community Setting: Prevalence, Risk Factors, and Composition of Gut Microbiome.Frontiers in microbiology · 2020Article
- Review
- Microbiome and Antimicrobial Resistance Gene Dynamics in International Travelers.Emerging infectious diseases · 2019Article
- Article
- Understanding the Epidemiology of Multi-Drug Resistant Gram-Negative Bacilli in the Middle East Using a One Health Approach.Frontiers in microbiology · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesThis study aims to assess the association between patient contact and intestinal carriage of multidrug-resistant organisms (MDRO) by sampling healthcare personnel (HCP) and staff without patient contact.
methodsFor this observational study, we recruited 400 HCP who worked in our 200-bed research hospital and 400 individuals without patient contact between November 2013 and February 2015. Participants submitted two self-collected perirectal swabs and a questionnaire. Swabs were processed for multidrug-resistant Gram-negative bacteria and vancomycin-resistant enterococci (VRE). Questionnaires explored occupational and personal risk factors for MDRO carriage.
resultsAmong 800 participants, 94.4% (755/800) submitted at least one swab, and 91.4% (731/800) also submitted questionnaires. Extended spectrum β-lactamase-producing organisms were recovered from 3.4% (26/755) of participants, and only one carbapenemase-producing organism was recovered. No VRE were detected. The potential exposure of 68.9% (250/363) of HCP who reported caring for MDRO-colonized patients did not result in a rate of MDRO carriage among HCP (4.0%; 15/379) significantly higher than that of staff without patient contact (3.2%; 12/376; p 0.55).
conclusionsThis is the largest US study of HCP intestinal MDRO carriage. The low colonization rate is probably reflective of local community background rates, suggesting that HCP intestinal colonization plays a minor role in nosocomial spread of MDROs in a non-outbreak setting.
trial registrationclinicaltrials.gov Identifier: NCT01952158.
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