Evidence map›Paper›PMID 28506527›Full record

ArticleBiophysical journal2017

Ancestral Interactions of Ribosomal RNA and Ribosomal Proteins.

Kathryn A Lanier, Poorna Roy, Dana M Schneider, Loren Dean Williams

Open access · hybridAbstract read
In one paragraph

Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Helicase-like functions in phosphate loop containing beta-alpha polypeptides.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. In the Beginning was a Mutualism - On the Origin of Translation.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kathryn A LanierSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia.
Poorna RoySchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia.
Dana M SchneiderSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia.
Loren Dean WilliamsSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia. Electronic address: loren.williams@chemistry.gatech.edu.
Georgia Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have proposed that the ancient ribosome increased in size during early evolution by addition of small folding-competent RNAs. In this Accretion Model, small RNAs and peptides were subsumed onto subunit surfaces, gradually encasing and freezing previously acquired components. The model predicts that appropriate rRNA fragments have inherited local autonomy of folding and local autonomy of assembly with ribosomal proteins (rProteins), and that the rProtein and rRNA are co-chaperones. To test these predictions, we investigate the rRNA interactions of rProtein uL23 and its tail, uL23

Indexed as

Evolution, MolecularModels, MolecularAmino Acid SequenceBacterial ProteinsBinding SitesCations, DivalentElectrophoretic Mobility Shift AssayEscherichia coliHydrogen BondingMagnesiumProtein BindingProtein DomainsProtein FoldingProtein Structure, SecondaryRibosomal ProteinsRNA, BacterialBacterial ProteinsCations, DivalentMagnesiumRibosomal ProteinsRNA, BacterialRNA, Ribosomal

Identifiers

PMID28506527
PMCPMC5529175
OpenAlexW2613920318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.