Evidence map›Paper›PMID 28506508›Full record

ArticleBurns : journal of the International Society for Burn Injuries2017

The influence of substance misuse on clinical outcomes following burn.

Sarah Rehou, Stephanie Mason, Jessie MacDonald, Ruxandra Pinto, Marc G Jeschke

Open access · greenAbstract read
In one paragraph

Article in Burns : journal of the International Society for Burn Injuries, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Impact of Preexisting Substance Use Disorders on Prolonged Opioid Use and Postoperative Complications After Burns.Journal of burn care & research : official publication of the American Burn Association · 2025
    Article
  2. Lower Admission Prealbumin and Albumin Levels in Unhoused Burn Patients Is a Marker for Poorer Outcomes.Journal of burn care & research : official publication of the American Burn Association · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. An Examination of Follow-up Services Received by Vulnerable Burn Populations: A Burn Model System National Database Study.Journal of burn care & research : official publication of the American Burn Association · 2020
    Article
  9. Contributors to the length-of-stay trajectory in burn-injured patients.Burns : journal of the International Society for Burn Injuries · 2018
    Article
  10. Trends 10 years after burn injury: A Burn Model System National Database study.Burns : journal of the International Society for Burn Injuries · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sarah RehouRoss Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Electronic address: ssrehou@gmail.com.
Stephanie MasonRoss Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Division of General Surgery, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: saamason@gmail.com.
Jessie MacDonaldFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: jessie.macdonald@mail.utoronto.ca.
Ruxandra PintoDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Electronic address: ruxandra.pinto@suannybrook.ca.
Marc G JeschkeRoss Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Division of Plastic and Reconstructive Surgery, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: marc.jeschke@sunnybrook.ca.
Sunnybrook Health Science Centre · CAUniversity of Toronto · CA

Funding

Hepatic ER stress contributes to morbidity and mortality after burn injury.R01GM087285 · NIGMS · SUNNYBROOK & WOMEN'S COLL HLTH SCIS CTR · PI BOEHNING, DARREN F, JESCHKE, MARC GERHARD · 2010 to 2018
$1.9M
NIGMS NIH HHS R01 GM087285
6 · The paper itself

Abstract

introductionOngoing increases in the prevalence of substance misuse among burn-injured patients necessitate a contemporary analysis of the association between substance misuse and clinical outcomes in burn-injured adults.

methodsWe conducted a retrospective cohort study of 1199 patients admitted to a regional burn center. History of substance misuse was derived from a prospective clinical registry and categorized as alcohol, illicit drug, or both. The primary outcome was hospital length of stay; association of substance misuse and inpatient complications were secondary outcomes. Multivariable logistic regression was used to model the association between categories of substance misuse and each outcome, adjusting for patient and injury characteristics.

resultsThe incidence of substance misuse was 34% overall. After adjustment for patient and injury characteristics, drug misuse was associated with a significantly longer length of stay (RR 1.12; 95% CI 1.00-1.25), as was alcohol misuse (RR 1.32; 95% CI 1.14-1.52), and drug/alcohol misuse (RR 1.34; 95% CI 1.16-1.56). Drug/alcohol misuse was associated with significantly higher rates of bacteremia (OR 3.84; 95% CI 1.83-8.04) and sepsis (OR 2.50; CI 1.13-5.53).

conclusionsA history of substance misuse is associated with an increased risk of inpatient complications and longer hospital stay. Providers should be cognizant of increased complications in this cohort with a view to improving outcomes.

Indexed as

AdultAlcoholismBacteremiaBurnsCellulitisCohort StudiesFemaleHumansIncidenceLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPneumoniaAlcohol-related disordersBurnsSubstance-related disorders

Identifiers

PMID28506508
PMCPMC7865207
OpenAlexW2611986006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.