Evidence map›Paper›PMID 28506313›Full record

ArticleHealth and quality of life outcomes2017

Latent variable mixture models to test for differential item functioning: a population-based analysis.

Xiuyun Wu, Richard Sawatzky, Wilma Hopman, Nancy Mayo, Tolulope T Sajobi, Juxin Liu, Jerilynn Prior, Alexandra Papaioannou, Robert G Josse, Tanveer Towheed and 2 more

Abstract readValidation Study
In one paragraph

Article in Health and quality of life outcomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Tree-based item-response theory model for evaluating differential item functioning in patient-reported outcome measures: a web-based R Shiny implementation.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  2. Tree-based latent variable model for assessing differential item functioning in patient-reported outcome measures: a simulation study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  3. Accuracy of mixture item response theory models for identifying sample heterogeneity in patient-reported outcomes: a simulation study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  4. Measurement invariance of the Seattle Angina Questionnaire in coronary artery disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  5. Article
  6. Demographic and functional differences among social security disability claimants.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  7. Article
  8. Article
  9. The use of latent variable mixture models to identify invariant items in test construction.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiuyun WuSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Richard SawatzkySchool of Nursing, Trinity Western University & Centre for Health Evaluation and Outcomes Sciences, Providence Health Care, Langley, BC, Canada.
Wilma HopmanDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.
Nancy MayoMcGill University Health Centre, Montréal, QC, Canada.
Tolulope T SajobiDepartment of Community Health Sciences & O'Brien Institute for Public Health, University of Calgary, Calgary, AB, Canada.
Juxin LiuDepartment of Mathematics and Statistics, University of Saskatchewan, Saskatoon, SK, Canada.
Jerilynn PriorDivision of Endocrinology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Alexandra PapaioannouDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Robert G JosseDepartment of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Tanveer TowheedDepartment of Medicine, Queen's University, Kingston, ON, Canada.
K Shawn DavisonFaculty of Graduate Studies, University of Victoria, Victoria, BC, Canada.
Lisa M LixDepartment of Community Health Sciences, University of Manitoba, S113-750 Bannatyne Ave, Winnipeg, MB, R3E 0W3, Canada. lisa.lix@umanitoba.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComparisons of population health status using self-report measures such as the SF-36 rest on the assumption that the measured items have a common interpretation across sub-groups. However, self-report measures may be sensitive to differential item functioning (DIF), which occurs when sub-groups with the same underlying health status have a different probability of item response. This study tested for DIF on the SF-36 physical functioning (PF) and mental health (MH) sub-scales in population-based data using latent variable mixture models (LVMMs).

methodsData were from the Canadian Multicentre Osteoporosis Study (CaMos), a prospective national cohort study. LVMMs were applied to the ten PF and five MH SF-36 items. A standard two-parameter graded response model with one latent class was compared to multi-class LVMMs. Multivariable logistic regression models with pseudo-class random draws characterized the latent classes on demographic and health variables.

resultsThe CaMos cohort consisted of 9423 respondents. A three-class LVMM fit the PF sub-scale, with class proportions of 0.59, 0.24, and 0.17. For the MH sub-scale, a two-class model fit the data, with class proportions of 0.69 and 0.31. For PF items, the probabilities of reporting greater limitations were consistently higher in classes 2 and 3 than class 1. For MH items, respondents in class 2 reported more health problems than in class 1. Differences in item thresholds and factor loadings between one-class and multi-class models were observed for both sub-scales. Demographic and health variables were associated with class membership.

conclusionsThis study revealed DIF in population-based SF-36 data; the results suggest that PF and MH sub-scale scores may not be comparable across sub-groups defined by demographic and health status variables, although effects were frequently small to moderate in size. Evaluation of DIF should be a routine step when analysing population-based self-report data to ensure valid comparisons amongst sub-groups.

Indexed as

Health StatusQuality of LifeSelf ReportAdultCanadaFemaleHumansLogistic ModelsMaleMental HealthMiddle AgedModels, StatisticalOsteoporosisProspective StudiesItem response theoryLatent class analysisMental healthPatient-reported outcome measuresPhysical functioningPopulation health

Identifiers

PMID28506313
PMCPMC5433241

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.