ArticleBMC neuroscience2017
Normobaric hypoxia overnight impairs cognitive reaction time.
Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Investigating Effects of Cold Water Hand Immersion on Selective Attention in Normobaric Hypoxia.International journal of environmental research and public health · 2019Trial
- Respiratory acclimatization and psychomotor performance after rapid ascent and during 3 weeks at 3,100 m-A prospective cohort study in healthy individuals.Frontiers in physiology · 2025Article
- Review
- A review of methods for assessment of cognitive function in high-altitude hypoxic environments.Brain and behavior · 2024Review
- Influence of short-term hypoxic exposure on spatial learning and memory function and brain-derived neurotrophic factor in rats-A practical implication to human's lost way.Frontiers in behavioral neuroscience · 2024Article
- The Question is Still Open: Is Supplemental Oxygen Enhancing Performance in Professional Athletes at High Altitude or Not?Sports medicine (Auckland, N.Z.) · 2023Article
- Altitude and Breathing during Sleep in Healthy Persons and Sleep Disordered Patients: A Systematic Review.Sleep science (Sao Paulo, Brazil) · 2023Review
- Cognition and Neuropsychological Changes at Altitude-A Systematic Review of Literature.Brain sciences · 2022Review
- Sleep loss effects on physiological and cognitive responses to systemic environmental hypoxia.Frontiers in physiology · 2022Review
- Exercise-Induced Elevated BDNF Level Does Not Prevent Cognitive Impairment Due to Acute Exposure to Moderate Hypoxia in Well-Trained Athletes.International journal of molecular sciences · 2020Article
- Effects on Cognitive Functioning of Acute, Subacute and Repeated Exposures to High Altitude.Frontiers in physiology · 2018Article
- Changes of hemodynamic and cerebral oxygenation after exercise in normobaric and hypobaric hypoxia: associations with acute mountain sickness.Annals of occupational and environmental medicine · 2018Article
- The influence of hypoxia and prolonged exercise on attentional performance at high and extreme altitudes: A pilot study.PloS one · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImpaired reaction time in patients suffering from hypoxia during sleep, caused by sleep breathing disorders, is a well-described phenomenon. High altitude sleep is known to induce periodic breathing with central apneas and oxygen desaturations, even in perfectly healthy subjects. However, deficits in reaction time in mountaineers or workers after just some nights of hypoxia exposure are not sufficiently explored. Therefore, we aimed to investigate the impact of sleep in a normobaric hypoxic environment on reaction time divided by its cognitive and motoric components. Eleven healthy non acclimatized students (5f, 6m, 21 ± 2.1 years) slept one night at a simulated altitude of 3500 m in a normobaric hypoxic room, followed by a night with polysomnography at simulated 5500 m. Preexisting sleep disorders were excluded via BERLIN questionnaire. All subjects performed a choice reaction test (SCHUHFRIED RT, S3) at 450 m and directly after the nights at simulated 3500 and 5500 m.
resultsWe found a significant increase of cognitive reaction time with higher altitude (p = 0.026). No changes were detected in movement time (p = n.s.). Reaction time, the combined parameter of cognitive- and motoric reaction time, didn't change either (p = n.s.). Lower SpO
conclusionSleep in hypoxia does not seem to affect reaction time to simple tasks. The component of cognitive reaction time is increasingly delayed whereas motoric reaction time seems not to be affected. Low SpO
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