Evidence map›Paper›PMID 28505470›Full record

Trial reportBehaviour research and therapy2017

Pilot test of a novel food response and attention training treatment for obesity: Brain imaging data suggest actions shape valuation.

Eric Stice, Sonja Yokum, Harm Veling, Eva Kemps, Natalia S Lawrence

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03557710 (Devaluing Energy-dense Foods for Cancer-control), which is not on this map. Cited by 56 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 5 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03557710 nacompletednot on this mapstarted 2018, after this paper: background citation

Devaluing Energy-dense Foods for Cancer-control: Translational Neuroscience

TypeinterventionalSponsorUniversity of OregonRan2018 to 2023Enrolled253ConditionsOverweight and Obesity, CancerArmsDevaluing energy-dense foods for cancer-control
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 5 syntheses or guidelines pooled it, 116 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Eric SticeOregon Research Institute, 1776 Millrace Drive, Eugene OR 97403 USA. Electronic address: estice@ori.org.
Sonja YokumOregon Research Institute, 1776 Millrace Drive, Eugene OR 97403 USA.
Harm VelingBehavioural Science Institute, Radboud University Nijmegen, PO Box 9104, 6500 HE Nijmegen, The Netherlands. Electronic address: h.veling@psych.ru.nl.
Eva KempsSchool of Psychology, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia. Electronic address: eva.kemps@flinders.edu.au.
Natalia S LawrenceSchool of Psychology, University of Exeter, Exeter EX4 4QG, UK. Electronic address: Natalia.lawrence@exeter.ac.uk.
Oregon Research Institute · USFlinders University · AURadboud University Nijmegen · NLUniversity of Exeter · GB

Funding

Relation of Consummatory and Anticipatory Food Reward to ObesityR01DK080760 · NIDDK · OREGON RESEARCH INSTITUTE · PI STICE, ERIC M, YOKUM, SONJA · 2009 to 2013
$3.3M
Effectiveness Trial of a Dissonance-Based Obesity Prevention ProgramR01HD071900 · NICHD · OREGON RESEARCH INSTITUTE · PI STICE, ERIC M · 2012 to 2016
$2.9M
Translational Neuroscience: Response Training for Obesity Treatment.R01DK112762 · NIDDK · STANFORD UNIVERSITY · PI STICE, ERIC M · 2017 to 2021
$2.4M
NICHD NIH HHS R01 HD071900NIDDK NIH HHS R01 DK080760NIDDK NIH HHS R01 DK112762
6 · The paper itself

Abstract

Elevated brain reward and attention region response, and weaker inhibitory region response to high-calorie food images have been found to predict future weight gain. These findings suggest that an intervention that reduces reward and attention region response and increases inhibitory control region response to such foods might reduce overeating. We conducted a randomized pilot experiment that tested the hypothesis that a multi-faceted food response and attention training with personalized high- and low-calorie food images would produce changes in behavioral and neural responses to food images and body fat compared to a control training with non-food images among community-recruited overweight/obese adults. Compared to changes observed in controls, completing the intervention was associated with significant reductions in reward and attention region response to high-calorie food images (Mean Cohen's d = 1.54), behavioral evidence of learning, reductions in palatability ratings and monetary valuation of high-calorie foods (p = 0.009, d's = 0.92), and greater body fat loss over a 4-week period (p = 0.009, d = 0.90), though body fat effects were not significant by 6-month follow-up. Results suggest that this multifaceted response and attention training intervention was associated with reduced reward and attention region responsivity to food cues, and a reduction in body fat. Because this implicit training treatment is both easy and inexpensive to deliver, and does not require top-down executive control that is necessary for negative energy balance obesity treatment, it may prove useful in treating obesity if future studies can determine how to create more enduring effects.

Indexed as

AttentionPsychotherapyAdipose TissueAdultBrainCuesFemaleFunctional NeuroimagingHumansInhibition, PsychologicalMagnetic Resonance ImagingMaleObesityOverweightPhotic StimulationPilot ProjectsAttentionAttention trainingFat lossfMRIObesity treatmentResponse trainingReward

Identifiers

PMID28505470
PMCPMC5656010
OpenAlexW2607209361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.