Trial reportJournal of the American Medical Informatics Association : JAMIA2017
Effect of health information exchange on recognition of medication discrepancies is interrupted when data charges are introduced: results of a cluster-randomized controlled trial.
Trial report in Journal of the American Medical Informatics Association : JAMIA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 7 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Medication Management Strategies at Hospital Admission: A Systematic Review and Meta-Analysis.Clinical and translational science · 2026Pooled it
- Effects of Health Information Exchanges in the Adult Inpatient Setting: a Systematic Review.Journal of general internal medicine · 2023Pooled it
- Reducing medication errors for adults in hospital settings.The Cochrane database of systematic reviews · 2021Pooled it
- A systematic literature review of LASA error interventions.British journal of clinical pharmacology · 2021Pooled it
- Routine Health Information System (RHIS) improvements for strengthened health system management.The Cochrane database of systematic reviews · 2020Pooled it
- The benefits of health information exchange: an updated systematic review.Journal of the American Medical Informatics Association : JAMIA · 2018Pooled it
- Findings from 2017 on Health Information ManagementYearbook of medical informatics · 2018Pooled it
- Health Information Exchange between Specialists and General Practitioners Benefits Rural Patients.Applied clinical informatics · 2021Trial
- Best possible medication history interview guide: a rapid scoping review.BMJ open quality · 2026Article
- The digital divide among U.S. Hospitals delivering health services to populations with high social disparities.Frontiers in digital health · 2026Article
- Clinicians' use of Health Information Exchange technologies for medication reconciliation in the U.S. Department of Veterans Affairs: a qualitative analysis.BMC health services research · 2024Article
- Data Consistency of Two National Registries in Iran: A Preliminary Assessment to Health Information Exchange.Archives of Iranian medicine · 2024Article
- Article
- Interprofessional survey on medication reconciliation activities in the US Department of Veterans' Affairs: development and validation of an Implementation Readiness Questionnaire.BMJ open quality · 2022Article
- Trends in user-initiated health information exchange in the inpatient, outpatient, and emergency settings.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- Impact of electronic health records on predefined safety outcomes in patients admitted to hospital: a scoping review.BMJ open · 2021Article
- Interventions to reduce medication errors in adult medical and surgical settings: a systematic review.Therapeutic advances in drug safety · 2020Review
- Key Factors Affecting Ambulatory Care Providers' Electronic Exchange of Health Information With Affiliated and Unaffiliated Partners: Web-Based Survey Study.JMIR medical informatics · 2019Article
- Article
- Health systems' use of enterprise health information exchange vs single electronic health record vendor environments and unplanned readmissions.Journal of the American Medical Informatics Association : JAMIA · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 1 country.
Funding
Abstract
objectivesTo determine the effect of health information exchange (HIE) on medication prescribing for hospital inpatients in a cluster-randomized controlled trial, and to examine the prescribing effect of availability of information from a large pharmacy insurance plan in a natural experiment.
methodsPatients admitted to an urban hospital received structured medication reconciliation by an intervention pharmacist with (intervention) or without (control) access to a regional HIE. The HIE contained prescribing information from the largest hospitals and pharmacy insurance plan in the region for the first 10 months of the study, but only from the hospitals for the last 21 months, when data charges were imposed by the insurance plan. The primary endpoint was discrepancies between preadmission and inpatient medication regimens, and secondary endpoints included adverse drug events (ADEs) and proportions of rectified discrepancies.
resultsOverall, 186 and 195 patients were assigned to intervention and control, respectively. Patients were 60 years old on average and took a mean of 7 medications before admission. There was no difference between intervention and control in number of risk-weighted discrepancies (6.4 vs 5.8, P = .452), discrepancy-associated ADEs (0.102 vs 0.092 per admission, P = .964), or rectification of discrepancies (0.026 vs 0.036 per opportunity, P = .539). However, patients who received medication reconciliation with pharmacy insurance data available had more risk-weighted medication discrepancies identified than those who received usual care (8.0 vs 5.9, P = .038). DISCUSSION AND
conclusionHIE may improve outcomes of medication reconciliation. Charging for access to medication information interrupts this effect. Efforts are needed to understand and increase prescribers' rectification of medication discrepancies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.