Evidence map›Paper›PMID 28505275›Full record

ArticleAmerican journal of epidemiology2017

Maternal Stressors and Social Support and Risks of Delivering Babies With Gastroschisis or Hypospadias.

Suzan L Carmichael, Chen Ma, Sarah Tinker, Gary M Shaw, National Birth Defects Prevention Study

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Gastroschisis and Cumulative Stressor Exposures.Epidemiology (Cambridge, Mass.) · 2018
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Suzan L CarmichaelDepartment of Pediatrics, School of Medicine, Stanford University, Stanford, California.
Chen MaDepartment of Pediatrics, School of Medicine, Stanford University, Stanford, California.
Sarah TinkerNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia.
Gary M ShawDepartment of Pediatrics, School of Medicine, Stanford University, Stanford, California.
National Birth Defects Prevention Study
Stanford University · USNational Center on Birth Defects and Developmental Disabilities · US

Funding

California Center of the NBDPS - Finding Causes and Preventives of Birth DefectsU01DD000489 · DD · STANFORD UNIVERSITY · PI SHAW, GARY C. · 2009 to 2013
$4.3M
Intramural CDC HHS CC999999NCBDD CDC HHS U01 DD000489
6 · The paper itself

Abstract

We examined the association of maternal stressful life events and social support with risks of gastroschisis and hypospadias, using data from the National Birth Defects Prevention Study, a population-based case-control study of US births taking place in 2006-2011. We examined maternal self-reports of 7 life events and 3 sources of social support during the periconceptional period among mothers of 593 gastroschisis cases, 1,142 male hypospadias cases, and 4,399 nonmalformed controls. Responses to the questions on stressful life events were summed to form an index (higher is worse), as were responses to questions on social support (higher is better). We used logistic regression to estimate adjusted odds ratios and 95% confidence intervals. The adjusted odds ratios for gastroschisis for a 4-point increase in the stress index were 3.5 (95% confidence interval (CI): 2.6, 4.8) among nonteenage mothers (age ≥20 years) and 1.0 (95% CI: 0.5, 1.7) among teenage mothers (age <20 years). The odds ratio for hypospadias (among all mothers) was 0.8 (95% CI: 0.7, 1.1). Adjusted odds ratios for a social support score of 3 (versus 0) in the 3 respective groups were 0.6 (95% CI: 0.4, 1.0), 1.0 (95% CI: 0.5, 2.3), and 0.6 (95% CI: 0.4, 0.9). Given the lack of prior research on these outcomes and stress, results should be interpreted with caution.

Indexed as

Social SupportAdultCase-Control StudiesFemaleGastroschisisHumansHypospadiasInfant, NewbornLife Change EventsLogistic ModelsMaleMothersOdds RatioPregnancyPregnancy ComplicationsRisk Factorsbirth defectsgastroschisishypospadiaspregnancystress

Identifiers

PMID28505275
PMCPMC5630491
OpenAlexW2612685018

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.