Evidence map›Paper›PMID 28504641›Full record

ArticleeLife2017

Helical jackknives control the gates of the double-pore K

Marina Diskowski, Ahmad Reza Mehdipour, Dorith Wunnicke, Deryck J Mills, Vedrana Mikusevic, Natalie Bärland, Jan Hoffmann, Nina Morgner, Heinz-Jürgen Steinhoff, Gerhard Hummer and 2 more

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. TrkA ofMicrobiology (Reading, England) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. c-di-AMP determines the hierarchical organization of bacterial RCK proteins.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. A channel profile report of the unusual KThe Journal of general physiology · 2019
    Article
  14. The KdpFABC complex - KMolecular membrane biology · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Cryo-EM structures of KdpFABC suggest a KNature communications · 2018
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marina DiskowskiInstitute of Biochemistry, Goethe-University, Frankfurt, Germany.
Ahmad Reza MehdipourDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt, Germany.
Dorith WunnickeInstitute of Biochemistry, Goethe-University, Frankfurt, Germany.
Deryck J MillsDepartment of Structural Biology, Max Planck Institute of Biophysics, Frankfurt, Germany.
Vedrana MikusevicInstitute of Biochemistry, Goethe-University, Frankfurt, Germany.
Natalie BärlandInstitute of Biochemistry, Goethe-University, Frankfurt, Germany.
Jan HoffmannInstitute for Physical and Theoretical Chemistry, Goethe-University, Frankfurt, Germany.
Nina MorgnerInstitute for Physical and Theoretical Chemistry, Goethe-University, Frankfurt, Germany.ORCID 0000-0002-1872-490X
Heinz-Jürgen SteinhoffDepartment of Physics, University of Osnabrück, Osnabrück, Germany.
Gerhard HummerDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt, Germany.
Janet VonckDepartment of Structural Biology, Max Planck Institute of Biophysics, Frankfurt, Germany.ORCID 0000-0001-5659-8863
Inga HäneltInstitute of Biochemistry, Goethe-University, Frankfurt, Germany.ORCID 0000-0003-1495-3163

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K

Indexed as

Adenosine DiphosphateAdenosine TriphosphateBacterial ProteinsCation Transport ProteinsCryoelectron MicroscopyElectron Spin Resonance SpectroscopyMolecular Dynamics SimulationVibrio alginolyticusAdenosine DiphosphateAdenosine TriphosphateBacterial ProteinsCation Transport ProteinsKtrB protein, Bacteriabiochemistrybiophysicscryo-electron microscopyE. coliligand-gated ion channelMD simulationsmembrane transportpotassium transportpulsed EPRstructural biology

Identifiers

PMID28504641
PMCPMC5449183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.