ArticleAngewandte Chemie (International ed. in English)2017
Plasmonic-Based Electrochemical Impedance Imaging of Electrical Activities in Single Cells.
Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Optical Detection of Cellular Signals at Material Interfaces.Advanced healthcare materials · 2026Review
- Real-Time and Spatially Resolved Analysis of Ion (De)Intercalation in Nickel Hexacyanoferrate Nanofilms Using Plasmonic Electrochemical Microscopy.Analytical chemistry · 2026Article
- Article
- Plasmonic imaging of living pancreatic beta-cell networks.Scientific reports · 2026Article
- Deep Learning Enhanced Label-Free Action Potential Detection Using Plasmonic-Based Electrochemical Impedance Microscopy.Analytical chemistry · 2024Article
- Review
- Plasmonic Scattering Microscopy for Label-Free Imaging of Molecular Binding Kinetics: From Single Molecules to Single Cells.Chemistry methods : new approaches to solving problems in chemistry · 2023Article
- Plasmonic imaging of the layer-dependent electrocatalytic activity of two-dimensional catalysts.Nature communications · 2022Article
- Optical Tracking of Surfactant-Tuned Bacterial Adhesion: a Single-Cell Imaging Study.Applied and environmental microbiology · 2022Article
- Optical Electrophysiology: Toward the Goal of Label-Free Voltage Imaging.Journal of the American Chemical Society · 2021Article
- Graphene Electric Field Sensor Enables Single Shot Label-Free Imaging of Bioelectric Potentials.Nano letters · 2021Article
- Article
- High-resolution impedance mapping using electrically activated quantitative phase imaging.Light, science & applications · 2021Article
- Article
- Label-free optical detection of bioelectric potentials using electrochromic thin films.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Surface Plasmon Resonance Microscopy: From Single-Molecule Sensing to Single-Cell Imaging.Angewandte Chemie (International ed. in English) · 2020Review
- Plasmonic imaging of subcellular electromechanical deformation in mammalian cells.Journal of biomedical optics · 2019Article
- Nanoscale electrochemical kinetics & dynamics: the challenges and opportunities of single-entity measurements.Faraday discussions · 2018Article
- Imaging Action Potential in Single Mammalian Neurons by Tracking the Accompanying Sub-Nanometer Mechanical Motion.ACS nano · 2018Article
- Electrochemical impedance spectroscopy of single Au nanorods.Chemical science · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Studying electrical activities in cells, such as action potential and its propagation in neurons, requires a sensitive and non-invasive analytical tool that can image local electrical signals with high spatial and temporal resolutions. Here we report a plasmonic-based electrochemical impedance imaging technique to study transient electrical activities in single cells. The technique is based on the conversion of the electrical signal into a plasmonic signal, which is imaged optically without labels. We demonstrate imaging of the fast initiation and propagation of action potential within single neurons, and validate the imaging technique with the traditional patch clamp technique. We anticipate that the plasmonic imaging technique will contribute to the study of electrical activities in various cellular processes.
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