Trial reportJournal of child psychology and psychiatry, and allied disciplines2017
Family-based promotion of mental health in children affected by HIV: a pilot randomized controlled trial.
Trial report in Journal of child psychology and psychiatry, and allied disciplines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01509573 (Family-Based Prevention of Mental Health Problems in HIV/AIDS-Affected Children), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Family-Based Prevention of Mental Health Problems in HIV/AIDS-Affected Children (R34MH084679-01A1)
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Delivering a family-based child mental health promotion program among two resettled refugee communities during the COVID-19 pandemic: Lessons learned in a hybrid type II implementation-effectiveness randomized controlled trial.American journal of community psychology · 2026Trial
- Trajectories of perinatal depression among women living with HIV in Uganda.Journal of global health · 2024Trial
- Trial
- Effect of a home-visiting parenting program to promote early childhood development and prevent violence: a cluster-randomized trial in Rwanda.BMJ global health · 2021Trial
- Promoting parent-child relationships and preventing violence via home-visiting: a pre-post cluster randomised trial among Rwandan families linked to social protection programmes.BMC public health · 2020Trial
- Family-Based Mental Health Promotion for Somali Bantu and Bhutanese Refugees: Feasibility and Acceptability Trial.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020Trial
- Family-centered interventions for people with substance use disorders in low-and middle-income country settings: a scoping review.The International journal on drug policy · 2026Article
- The impact of intergenerational transmission of stigma on the psychological development of minors with HIV-positive parents.Frontiers in psychology · 2026Review
- Adolescents' Mental Well-Being and Social Support: Mixed Methods Study.International journal of mental health nursing · 2025Article
- Communication with children about parental bipolar disorder: a qualitative interview study.International journal of bipolar disorders · 2025Article
- Mental health challenges among adolescents and young adults with perinatally acquired HIV: Key findings from the I'mPossible program in India.PLOS mental health · 2025Article
- Article
- Delivering therapy over telephone in a humanitarian setting: a pilot randomized controlled trial of common elements treatment approach (CETA) with Syrian refugee children in Lebanon.Conflict and health · 2024Article
- Mental health outcomes of offspring exposed to parental intimate partner violence in Rwanda.BMC pediatrics · 2024Article
- Promotive and preventive interventions for adolescent mental health in Sub-Saharan Africa: a combined scoping and systematic review.BMJ public health · 2023Article
- Applying Human-Centered Design in Global Mental Health to Improve Reach Among Underserved Populations in the United States and India.Global health, science and practice · 2023Article
- Interventions addressing family violence and mental illness or substance use in low- and middle-income countries: A systematic review.Global mental health (Cambridge, England) · 2023Review
- Prevalence of stressful life events and associations with symptoms of depression, anxiety, and post-traumatic stress disorder among people entering care for HIV in Cameroon.Journal of affective disorders · 2022Article
- Effects of a Multilevel Resilience-Based Intervention on Mental Health for Children Affected by Parental HIV: A Cluster Randomized Controlled Trial.Journal of child and family studies · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundChildren affected by HIV are at risk for poor mental health. We conducted a pilot randomized controlled trial (RCT) of the Family Strengthening Intervention (FSI-HIV), a family home-visiting intervention to promote mental health and improve parent-child relationships in families with caregivers living with HIV, hypothesizing that child and family outcomes would be superior to usual care social work services.
methodsEighty two families (N = 170 children, 48.24% female; N = 123 caregivers, 68.29% female) with at least one HIV-positive caregiver (n = 103, 83.74%) and school-aged child (ages 7-17) (HIV+ n = 21, 12.35%) were randomized to receive FSI-HIV or treatment-as-usual (TAU). Local research assistants blind to treatment conducted assessments of child mental health, parenting practices, and family functioning at baseline, post-intervention, and 3-month follow-up. Multilevel modeling assessed effects of FSI-HIV on outcomes across three time points.
trial registrationNCT01509573, 'Pilot Feasibility Trial of the Family Strengthening Intervention in Rwanda (FSI-HIV-R).' https://clinicaltrials.gov/ct2/show/;NCT01509573?term=Pilot+Feasibility+Trial+of+the+Family+Strengthening+Intervention+in+Rwanda+%28FSI-HIV-R%29&rank=1.
resultsAt 3-month follow-up, children in FSI-HIV showed fewer symptoms of depression compared to TAU by both self-report (β = -.246; p = .009) and parent report (β = -.174; p = .035) but there were no significant differences by group on conduct problems, functional impairment, family connectedness, or parenting.
conclusionsFamily-based prevention has promise for reducing depression symptoms in children affected by HIV. Future trials should examine the effects of FSI-HIV over time in trials powered to examine treatment mediators.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.