'Pragmatic' and 'explanatory' attitudes to randomised trials.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Use of pragmatic randomized trials in multiple sclerosis: A systematic overview.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024
   Pooled it
2. Are trials of psychological and psychosocial interventions for schizophrenia and psychosis included in the NICE guidelines pragmatic? A systematic review.PloS one · 2019
   Pooled it
3. Motivational interviewing for reducing rehospitalisation and improving patient activation among patients with heart failure or chronic obstructive pulmonary disease: a randomised controlled trial.BMJ open · 2025
   Trial
4. Effect of Wearing Glasses on Risk of Infection With SARS-CoV-2 in the Community: A Randomized Clinical Trial.JAMA network open · 2022
   Trial
5. A Comparison of Methods for Testing and Implementing Community Health Interventions in Childhood: A Realist Review.Children (Basel, Switzerland) · 2025
   Review
6. Multicentre pragmatic randomised controlled feasibility trial of fertiShare, a brief eLearning course to increase fertility staff performance when sharing bad news with their patients - a protocol.BMJ open · 2025
   Article
7. SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials.BMJ (Clinical research ed.) · 2025
   Article
8. Social prescribing to improve health and well-being of patients presenting with non-medical health related social needs in primary care: Study protocol of a multi-center randomized controlled pragmatic feasibility trial.PloS one · 2025
   Article
9. Randomised controlled trial of HOYA one-day multifocal contact lenses: The HOMCL trial.Heliyon · 2024
   Article
10. Methodological challenges in pragmatic trials in Alzheimer's disease and related dementias: Opportunities for improvement.Clinical trials (London, England) · 2022
    Article
11. Research and Scholarly Methods: Pragmatic Clinical Trials.Journal of the American College of Clinical Pharmacy : JACCP · 2022
    Article
12. [Benefit assessment of digital health applications-challenges and opportunities].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2021
    Review
13. Framework for the development and evaluation of complex interventions: gap analysis, workshop and consultation-informed update.Health technology assessment (Winchester, England) · 2021
    Article
14. Building internal capacity in pragmatic trials: a workshop for program scientists at the US National Cancer Institute.Trials · 2019
    Article
15. Embedding patient- and public health-oriented research in a national health service: the GISSI experience.Journal of the Royal Society of Medicine · 2019
    Article
16. Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol.Trials · 2018
    Article
17. Clinical drug trials in general practice: how well are external validity issues reported?BMC family practice · 2017
    Review
18. Patient and public involvement in pragmatic trials: online survey of corresponding authors of published trials.CMAJ open
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as