Evidence map›Paper›PMID 28503732›Full record

ArticleJournal of magnetic resonance imaging : JMRI2018

Imaging short-lived reactive oxygen species (ROS) with endogenous contrast MRI.

Rong-Wen Tain, Alessandro M Scotti, Weiguo Li, Xiaohong Joe Zhou, Kejia Cai

Open access · greenAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Quantitative imaging in medicine and surgery · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Real-timeBiomedical optics express · 2023
    Article
  8. Article
  9. Article
  10. TowardBiosensors · 2022
    Review
  11. Review
  12. CombiningFrontiers in neuroscience · 2022
    Article
  13. Article
  14. In Vivo Proton Exchange Rate (kJournal of magnetic resonance imaging : JMRI · 2021
    Article
  15. Article
  16. Decreased Subcortical T2 FLAIR Signal Associated with Seizures.AJNR. American journal of neuroradiology · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Oxidative stress measured in vivo without an exogenous contrast agent using QUEST MRI.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rong-Wen TainDepartment of Radiology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Alessandro M ScottiDepartment of Radiology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Weiguo LiResearch Resource Center, University of Illinois at Chicago, Chicago, Illinois, USA.
Xiaohong Joe ZhouDepartment of Radiology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Kejia CaiDepartment of Radiology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
University of Illinois Chicago · USNorthwestern University · US

Funding

Take pictures of short-lived ROS with endogenous contrast MRIR21EB023516 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CAI, KEJIA · 2017 to 2018
$440k
NIBIB NIH HHS R21 EB023516
6 · The paper itself

Abstract

purposeTo characterize the relaxation properties of reactive oxygen species (ROS) for the development of endogenous ROS contrast magnetic resonance imaging (MRI). MATERIALS AND

methodsROS-producing phantoms and animal models were imaged at 9.4T MRI to obtain T

resultspH and temperature changes in treated egg white samples were insignificant (<0.1 unit and <1°C, respectively). T

conclusionWe demonstrated in the study that endogenous ROS MRI based on the paramagnetic effect has sensitivity for in vitro and in vivo applications. LEVEL OF EVIDENCE: 2 Technical Efficacy Stage: 2 J. Magn. Reson. Imaging 2018;47:222-229.

Indexed as

Magnetic Resonance ImagingAnimalsBrainContrast MediaDisease Models, AnimalEgg WhiteGadolinium DTPAHydrogen-Ion ConcentrationHydrogen PeroxideHydroxyl RadicalImage EnhancementMaleMiceOxygenPhantoms, ImagingReactive Oxygen SpeciesContrast MediaGadolinium DTPAHydrogen PeroxideHydroxyl RadicalOxygenReactive Oxygen SpeciesRotenoneSerum Albumin, Bovinefree radicalsMRIparamagnetic effectreactive oxygen speciesrelaxation time

Identifiers

PMID28503732
PMCPMC5752154
OpenAlexW2616629882

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.