Evidence map›Paper›PMID 28503718›Full record

ArticleLasers in medical science2017

Photodithazine photodynamic effect on viability of 9L/lacZ gliosarcoma cell line.

Leticia C Fontana, Juliana G Pinto, André H C Pereira, Cristina P Soares, Leandro J Raniero, Juliana Ferreira-Strixino

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leticia C FontanaLaboratório de Terapia Fotodinâmica, Instituto de Pesquisa e Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), Avenida Shishima Hifumi, 2911, São José dos Campos, SP, 12400-000, Brazil.
Juliana G PintoLaboratório de Terapia Fotodinâmica, Instituto de Pesquisa e Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), Avenida Shishima Hifumi, 2911, São José dos Campos, SP, 12400-000, Brazil.
André H C PereiraLaboratório de Terapia Fotodinâmica, Instituto de Pesquisa e Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), Avenida Shishima Hifumi, 2911, São José dos Campos, SP, 12400-000, Brazil.
Cristina P SoaresLaboratório Dinâmica dos Compartimentos Celulares, Instituto de Pesquisa e Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), São José dos Campos, SP, 12400-000, Brazil.
Leandro J RanieroLaboratório de Nanossensores, Instituto de Pesquisa e Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), São José dos Campos, SP, 12400-000, Brazil.
Juliana Ferreira-StrixinoLaboratório de Terapia Fotodinâmica, Instituto de Pesquisa e Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), Avenida Shishima Hifumi, 2911, São José dos Campos, SP, 12400-000, Brazil. juferreira@univap.br.
Universidade do Vale do Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even with the advances of conventional treatment techniques, the nervous system cancer prognosis is still not favorable to the patient which makes alternative therapies needed to be studied. Photodynamic therapy (PDT) is presented as a promising therapy, which employs a photosensitive (PS) agent, light wavelength suitable for the PS agent, and molecular oxygen, producing reactive oxygen species in order to induce cell death. The aim of this study is to observe the PDT action in gliosarcoma cell using a chlorin (Photodithazine, PDZ). The experiments were done with 9L/lacZ lineage cells, grown in a DMEM medium supplemented with 10% fetal bovine serum and 1% penicillin/streptomycin solution and put in a culture chamber at 37 °C with an atmosphere of 5% CO

Indexed as

Cell DeathCell Line, TumorCell ShapeCell SurvivalGliosarcomaGlucosamineHumansMitochondriaPhotochemotherapyPhotosensitizing AgentsTrypan BlueGlucosamineN-methylglucosaminePhotosensitizing AgentsTrypan BlueBrain cancerChlorinGliosarcomaPhotodynamic therapy

Identifiers

PMID28503718
OpenAlexW2613535879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.