Evidence map›Paper›PMID 28503548›Full record

ArticleFrontiers in bioengineering and biotechnology2017

Exploiting Self-organization in Bioengineered Systems: A Computational Approach.

Delin Davis, Anna Doloman, Gregory J Podgorski, Elizabeth Vargis, Nicholas S Flann

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Directing Multicellular Organization by Varying the Aspect Ratio of Soft Hydrogel Microwells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Delin DavisComputer Science Department, Utah State University, Logan, UT, USA.
Anna DolomanDepartment of Biological Engineering, Utah State University, Logan, UT, USA.
Gregory J PodgorskiDepartment of Biology, Utah State University, Logan, UT, USA.
Elizabeth VargisDepartment of Biological Engineering, Utah State University, Logan, UT, USA.
Nicholas S FlannComputer Science Department, Utah State University, Logan, UT, USA.

Funding

Quantitative Systems BiologyP50GM076547 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI BALIGA, NITIN S · 2006 to 2016
$30.6M
NIGMS NIH HHS P50 GM076547
6 · The paper itself

Abstract

The productivity of bioengineered cell factories is limited by inefficiencies in nutrient delivery and waste and product removal. Current solution approaches explore changes in the physical configurations of the bioreactors. This work investigates the possibilities of exploiting self-organizing vascular networks to support producer cells within the factory. A computational model simulates

Indexed as

agent-based modelingbiomanufacturingmulticellular modelingself-organizationvasculogenesis

Identifiers

PMID28503548
PMCPMC5408088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.