ArticleAnnals of coloproctology2017
Prognostic Significance of Mucinous Histologic Subtype on Oncologic Outcomes in Patients With Colorectal Cancer.
Article in Annals of coloproctology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comprehensive Overview of Molecular, Imaging, and Therapeutic Challenges in Rectal Mucinous Adenocarcinoma.International journal of molecular sciences · 2025Pooled it
- Clinicopathological and prognostic features of colorectal mucinous adenocarcinomas: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- The Heterogeneity of Mucinous Colorectal Adenocarcinoma-Histologic and Molecular Phenotypes Drive Prognostic Outcomes.Cancers · 2026Article
- Review
- Clinical and Histopathological Characteristics of Colorectal Cancer in Iraq between 2015-2021.Archives of Razi Institute · 2022Article
- Clinical significance of mucinous component in colorectal adenocarcinoma: a propensity score-matched study.BMC cancer · 2021Article
- Pattern of distant metastases and predictive nomograms in colorectal mucinous adenocarcinoma: a SEER analysis.Journal of gastrointestinal oncology · 2021Article
- Article
- Multi gene mutation signatures in colorectal cancer patients: predict for the diagnosis, pathological classification, staging and prognosis.BMC cancer · 2021Article
- Clinicopathological Features and Survival of Signet-Ring Cell Carcinoma and Mucinous Adenocarcinoma of Right Colon, Left Colon, and Rectum.Pathology oncology research : POR · 2021Article
- Clinical impact of non-predominant histopathological subtypes on the long-term prognosis of colorectal cancer patients in Japan.International journal of colorectal disease · 2020Article
- Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer.Molecular medicine reports · 2020Article
- Clinicopathological characteristics and prognosis of colorectal mucinous adenocarcinoma and nonmucinous adenocarcinoma: a surveillance, epidemiology, and end results (SEER) population-based study.Annals of translational medicine · 2020Article
- Incidence and prognosis of pulmonary metastasis in colorectal cancer: a population-based study.International journal of colorectal disease · 2020Article
- Predictive Significance of Mucinous Histology on Pathologic Complete Response Rate Following Capecitabine-Based Neoadjuvant Chemoradiation in Rectal Cancer: a Comparative Study.Journal of gastrointestinal cancer · 2019Article
- SCF/c-KIT Signaling Increased Mucin2 Production by Maintaining Atoh1 Expression in Mucinous Colorectal Adenocarcinoma.International journal of molecular sciences · 2018Article
- Mucinous Subtype in Patients With Colorectal Cancer.Annals of coloproctology · 2017Article
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6 authors.
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Abstract
purposeMucinous adenocarcinomas account for about 10% of all colorectal cancers. This study aimed to investigate the prognostic impact of mucinous histologic subtype on oncologic outcomes in patients with colorectal cancer.
methodsThis retrospective study was performed at two large tertiary university hospitals. We analyzed the characteristics, prognostic factors, and survival of patients with colorectal cancer who were treated and followed up between 2000 and 2013.
resultsTotally, 144 of 1,268 patients with a colorectal adenocarcinoma (11.4%) had mucinous histologic subtype. Statistically significant results found in this research are as follows: Mucinous histologic subtype tended to present in younger patients and to have larger tumor size, higher histologic grade, higher node stage, larger number of positive nodes, and higher rate of perineural invasion compared to nonmucinous histologic subtype. On the univariate analysis, mucinous subtype was a prognostic factor for disease-free and overall survival. On the multivariate analysis, primary tumor location, node stage and lymphatic-vascular invasion were independent prognostic factors for the local control rate. Rectal tumor location, higher disease stage, tumor grade II, and presence of lymphatic-vascular invasion had negative influences on disease-free survival, as did rectal tumor location, higher disease stage and presence of lymphatic-vascular invasion on overall survival.
conclusionMucinous histologic subtype was associated with some adverse pathologic features in patients with colorectal cancer; however, it was not an independent prognostic factor for oncologic outcome.
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