Evidence map›Paper›PMID 28503150›Full record

ArticleFrontiers in physiology2017

Dental Pulp Cells Isolated from Teeth with Superficial Caries Retain an Inflammatory Phenotype and Display an Enhanced Matrix Mineralization Potential.

Hanaa Alkharobi, James Beattie, Josie Meade, Deirdre Devine, Reem El-Gendy

Abstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hanaa AlkharobiDivision of Oral Biology, Leeds School of Dentistry, St. James University Hospital, University of LeedsLeeds, UK.
James BeattieDivision of Oral Biology, Leeds School of Dentistry, St. James University Hospital, University of LeedsLeeds, UK.
Josie MeadeDivision of Oral Biology, Leeds School of Dentistry, St. James University Hospital, University of LeedsLeeds, UK.
Deirdre DevineDivision of Oral Biology, Leeds School of Dentistry, St. James University Hospital, University of LeedsLeeds, UK.
Reem El-GendyDivision of Oral Biology, Leeds School of Dentistry, St. James University Hospital, University of LeedsLeeds, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

We have isolated dental pulp cells (DPCs) from three healthy (hDPCs) and three carious (cDPCs) donors and shown that compared to hDPCs cells isolated from superficial carious lesions show higher clonogenic potential; show an equivalent proportion of cells with putative stem cell surface markers; show enhanced matrix mineralization capability; have enhanced angiogenic marker expression and retain the inflammatory phenotype

Indexed as

dental pulp cells (DPCs)inflammationodontogenesisosteogenesisregeneration

Identifiers

PMID28503150
PMCPMC5408163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.