ArticleJournal of neonatal nursing : JNN2017
Feeding intolerance, inflammation, and neurobehaviors in preterm infants.
Article in Journal of neonatal nursing : JNN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Comparative efficacy of different single drugs to prevent necrotizing enterocolitis in preterm infants: an update systematic review and network meta-analysis.Frontiers in nutrition · 2024Pooled it
- Phentolamine and B vitamins for feeding intolerance in late preterm infants: a randomised trial.Asia Pacific journal of clinical nutrition · 2024Trial
- Electrogastrography-Derived Mean Power Ratio as an Exploratory Objective Measure of Feeding Intolerance in Preterm Infants.Bioengineering (Basel, Switzerland) · 2026Article
- Postprandial decline in abdominal regional oxygen saturation is associated with feeding intolerance in preterm infants: a prospective cohort study.Frontiers in pediatrics · 2026Article
- Impact of Clinical Use of Probiotics on Preterm-Related Outcomes in Infants with Extremely Low Birth Weight.Nutrients · 2024Article
- Using a new human milk fortifier to optimize human milk feeding among very preterm and/or very low birth weight infants: a multicenter study in China.BMC pediatrics · 2024Article
- Frequency-specific electrogastrography as a non-invasive tool to measure gastrointestinal maturity in preterm infants.Scientific reports · 2022Article
- Feeding intolerance.Early human development · 2022Article
- Clinical efficacy of probiotics on feeding intolerance in preterm infants: a systematic review and meta-analysis.Translational pediatrics · 2022Article
- Necrotizing enterocolitis: It's not all in the gut.Experimental biology and medicine (Maywood, N.J.) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
purposeIdentifying relationships between feeding intolerance (FI), inflammation, and early measures of neurodevelopment may provide the basis for clinically relevant assessments for NICU clinicians and staff. The purpose of this secondary analysis was to examine the relationship of FI to inflammatory markers and/or neurobehaviors in the first week of life.
methodsThis was a retrospective, matched case-control design with data drawn from 114 infants born at ≤32 weeks gestation.
resultsEight infants developed FI prior to full enteral feedings. These infants were more likely to have dysregulated levels of cytokines, specifically IL6, and lower neurodevelopmental scores compared to infants without FI.
conclusionsResults suggest physiologic dysregulation and an immature nervous system may contribute to the phenomenon of FI in preterm infants. Further research to identify the role of the brain-gut-immune axis on FI and other GI complications in this population is warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.