Evidence map›Paper›PMID 28502823›Full record

ArticleThe Journal of allergy and clinical immunology2017

NIAID, NIEHS, NHLBI, and MCAN Workshop Report: The indoor environment and childhood asthma-implications for home environmental intervention in asthma prevention and management.

Diane R Gold, Gary Adamkiewicz, Syed Hasan Arshad, Juan C Celedón, Martin D Chapman, Ginger L Chew, Donald N Cook, Adnan Custovic, Ulrike Gehring, James E Gern and 21 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. A novel ambient air sampler for detection of allergens and endotoxin.The journal of allergy and clinical immunology. Global · 2026
    Article
  7. Article
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  10. Relationships between lung function, allergy, and wheezing in urban children.The Journal of allergy and clinical immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 4 countries.

Diane R GoldChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address: diane.gold@channing.harvard.edu.
Gary AdamkiewiczDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Syed Hasan ArshadDavid Hide Asthma and Allergy Research Centre, Isle of Wight, and Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Juan C CeledónDivision of Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, Pa.
Martin D ChapmanIndoor Biotechnologies, Charlottesville, Va.
Ginger L ChewCenters for Disease Control and Prevention (CDC), National Center for Environmental Health, Division of Environmental Hazards and Health Effects | Air Pollution and Respiratory Health Branch, Atlanta, Ga.
Donald N CookImmunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Adnan CustovicSection of Paediatrics and MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom.
Ulrike GehringInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
James E GernDepartments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
Christine C JohnsonDepartment of Public Health Sciences, Henry Ford Hospital & Health System, Detroit, Mich.
Suzanne KennedyDepartment of Pediatrics, NC Children's Hospital, University of North Carolina, Chapel Hill, NC.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Brian LeadererYale School of Public Health, Yale School of Medicine, Yale School of Forestry and Environmental Studies, Center for Perinatal, Pediatric and Environmental Epidemiology (CPPEE), New Haven, Conn.
Herman MitchellRho Federal Systems Division, Rho, Inc, Chapel Hill, NC.
Augusto A LitonjuaChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass.
Geoffrey A MuellerGenome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
George T O'ConnorPulmonary Center, Boston University School of Medicine, Boston, Mass.
Dennis OwnbyDivision of Allergy-Immunology and Rheumatology, Department of Pediatrics, Augusta University, Augusta, Ga.
Wanda PhipatanakulAsthma, Allergy and Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Victoria PerskyDivision of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Ill.
Matthew S PerzanowskiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY.
Clare D RamseyDepartments of Medicine and Community Health Sciences, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Päivi M SaloDivision of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Julie M SchwaningerDivision of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Joanne E SordilloChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass.
Avrum SpiraDivision of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Mass.
Shakira F SugliaDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Ga.
Alkis TogiasDivision of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Darryl C ZeldinDivision of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Elizabeth C MatsuiDivision of Pediatric Allergy/Immunology, Johns Hopkins University, Baltimore, Md.
National Institutes of Health · USBrigham and Women's Hospital · USBoston University · USHarvard University · USAsthma UK · GBAugusta University · USBoston Children's Hospital · USChildren's Hospital of Pittsburgh · USColumbia University · USDavid Hide Asthma and Allergy Research Centre · GBEmory University · USHenry Ford Health System · USIndoor Biotechnologies (United States) · USJohns Hopkins University · USNational Center for Environmental Health · USProvidence Center · USRho (United States) · USUniversity of Illinois Chicago · USUniversity of Manitoba · CAUniversity of North Carolina Hospitals · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Occupational Safety and Health, ERC, University of Illinois at ChicagoT42OH008672 · OH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BUCHANAN, SUSAN NATHALIE · 2005 to 2025
$32.7M
The Effect of Dog-Keeping and the Intestinal Microbiota on Immune DevelopmentP01AI089473 · NIAID · HENRY FORD HEALTH SYSTEM · PI LUKACS, NICHOLAS W · 2012 to 2024
$25.7M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUNGE-MORRIS, MELISSA A · 2014 to 2021
$10.1M
Structural and Functional Characterization of AllergensZIAES102906 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MUELLER, GEOFFREY · 2010 to 2025
$10.0M
Indoor Allergens And AsthmaZIAES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$8.5M
Intramural CDC HHS CC999999Intramural NIH HHS Z99 AI999999Medical Research Council G1000758Medical Research Council MR/K002449/2NCATS NIH HHS UL1 TR001863NIAID NIH HHS P01 AI089473NIEHS NIH HHS P30 ES020957NIOSH CDC HHS T42 OH008672
6 · The paper itself

Abstract

Environmental exposures have been recognized as critical in the initiation and exacerbation of asthma, one of the most common chronic childhood diseases. The National Institute of Allergy and Infectious Diseases; National Institute of Environmental Health Sciences; National Heart, Lung, and Blood Institute; and Merck Childhood Asthma Network sponsored a joint workshop to discuss the current state of science with respect to the indoor environment and its effects on the development and morbidity of childhood asthma. The workshop included US and international experts with backgrounds in allergy/allergens, immunology, asthma, environmental health, environmental exposures and pollutants, epidemiology, public health, and bioinformatics. Workshop participants provided new insights into the biologic properties of indoor exposures, indoor exposure assessment, and exposure reduction techniques. This informed a primary focus of the workshop: to critically review trials and research relevant to the prevention or control of asthma through environmental intervention. The participants identified important limitations and gaps in scientific methodologies and knowledge and proposed and prioritized areas for future research. The group reviewed socioeconomic and structural challenges to changing environmental exposure and offered recommendations for creative study design to overcome these challenges in trials to improve asthma management. The recommendations of this workshop can serve as guidance for future research in the study of the indoor environment and on environmental interventions as they pertain to the prevention and management of asthma and airway allergies.

Indexed as

Drug IndustryNational Heart, Lung, and Blood Institute (U.S.)National Institute of Allergy and Infectious Diseases (U.S.)National Institute of Environmental Health Sciences (U.S.)Organizations, NonprofitAir Pollution, IndoorAnimalsAsthmaBiomedical ResearchChildConsensus Development Conferences, NIH as TopicEnvironmental HealthFund RaisingHumansUnited StatesallergyAsthmachild healthclinical trialsenvironmental interventionindoor allergenspollutants

Identifiers

PMID28502823
PMCPMC5632590
OpenAlexW2611973547

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.