Evidence map›Paper›PMID 28502659›Full record

ArticleCurrent biology : CB2017

APC/C

Ahmed Rattani, Randy Ballesteros Mejia, Katherine Roberts, Maurici B Roig, Jonathan Godwin, Michael Hopkins, Manuel Eguren, Luis Sanchez-Pulido, Elwy Okaz, Sugako Ogushi and 7 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  9. Proceedings of the National Academy of Sciences of the United States of America · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Ahmed RattaniDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Randy Ballesteros MejiaNewcastle Fertility Centre, Centre for Life, Times Square, Newcastle upon Tyne NE1 4EP, UK; Wellcome Trust Centre for Mitochondrial Research, Institute for Genetic Medicine, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
Katherine RobertsDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Maurici B RoigDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Jonathan GodwinDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Michael HopkinsDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Manuel EgurenCell Division and Cancer Group, Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.
Luis Sanchez-PulidoMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.
Elwy OkazDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Sugako OgushiDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Magda WolnaDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Jean MetsonDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Alberto M PendásInstituto de Biología Molecular y Celular del Cáncer de Salamanca, CSIC-Universidad de Salamanca, 37007 Salamanca, Spain.
Marcos MalumbresCell Division and Cancer Group, Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.
Béla NovákDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Mary HerbertNewcastle Fertility Centre, Centre for Life, Times Square, Newcastle upon Tyne NE1 4EP, UK; Wellcome Trust Centre for Mitochondrial Research, Institute for Genetic Medicine, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
Kim NasmythDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. Electronic address: ashley.nasmyth@bioch.ox.ac.uk.
University of Oxford · GBCentro de Investigación del Cáncer · ESNewcastle University · GBUniversity of Edinburgh · GBWellcome Centre for Mitochondrial Research · GB

Funding

Medical Research Council MC_UU_12008/1Medical Research Council MR/J003603/1Wellcome Trust 096919
6 · The paper itself

Abstract

In mammalian females, germ cells remain arrested as primordial follicles. Resumption of meiosis is heralded by germinal vesicle breakdown, condensation of chromosomes, and their eventual alignment on metaphase plates. At the first meiotic division, anaphase-promoting complex/cyclosome associated with Cdc20 (APC/C

Indexed as

ChromosomesMeiosisAnaphase-Promoting Complex-CyclosomeAnimalsApc2 Subunit, Anaphase-Promoting Complex-CyclosomeAurora Kinase BAurora Kinase CCdc20 Proteinscdc25 PhosphatasesCDC2 Protein KinaseCdh1 ProteinsCell Cycle ProteinsCentromereChromosomal Proteins, Non-HistoneCohesinsFemaleAnapc2 protein, mouseAnaphase-Promoting Complex-CyclosomeApc2 Subunit, Anaphase-Promoting Complex-CyclosomeAurkb protein, mouseAurkc protein, mouseAurora Kinase BAurora Kinase CCdc20 protein, mouseCdc20 Proteinscdc25 PhosphatasesCDC2 Protein KinaseCdh1 ProteinsCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsFzr1 protein, mouseSeparaseSGOL2 protein, mouseaneuploidyAPC/C(Cdh1)aurora kinasecohesinmeiosisshugoshin-2

Identifiers

PMID28502659
PMCPMC5457479
OpenAlexW2612014302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.