Evidence map›Paper›PMID 28502539›Full record

ArticleJournal of vascular surgery2017

Racial differences in functional decline in peripheral artery disease and associations with socioeconomic status and education.

Mary M McDermott, Tamar S Polonsky, Melina R Kibbe, Lu Tian, Lihui Zhao, William H Pearce, Ying Gao, Jack M Guralnik

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of vascular surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Peripheral artery disease.Nature reviews. Disease primers · 2025
    Review
  9. ARTS is associated with vascular risk factors, MCI, dementia, and stroke.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Article
  11. Article
  12. Racial and Socioeconomic Health Disparities in Peripheral Artery Disease.Journal of the American Heart Association · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Mary M McDermottDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: mdm608@northwestern.edu.
Tamar S PolonskyDepartment of Medicine, University of Chicago, Chicago, Ill.
Melina R KibbeDepartment of Surgery, University of North Carolina School of Medicine, Chapel Hill, NC.
Lu TianDepartment of Biomedical Data Science, Stanford University, Stanford, Calif.
Lihui ZhaoDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
William H PearceDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill; Jesse Brown Veterans Affairs Medical Center, Chicago, Ill.
Ying GaoDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Jack M GuralnikDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Md.
Northwestern University · USJesse Brown VA Medical Center · USStanford University · USUniversity of Chicago · USUniversity of Maryland, Baltimore · USUniversity of North Carolina at Chapel Hill · US

Funding

Blood Markers of Vulnerability in High Risk Vascular PatientsR01HL089619 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2009 to 2012
$2.9M
Magnetic Resonance in Peripheral Arterial DiseaseR01HL083064 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2007 to 2010
$2.9M
Femoral Plaque Composition, Oxidative Stress, and Coronary EventsR01HL109244 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2011 to 2014
$2.7M
Inflammation and Peripheral Arterial Disease OutcomesR01HL076298 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2005 to 2008
$2.7M
Mechanisms of Disability in Peripheral Arterial DiseaseR01HL071223 · NHLBI · NORTHWESTERN UNIVERSITY · PI MCDERMOTT, MARY MCGRAE · 2002 to 2005
$2.7M
BLOOD FACTORS AND PERIPHERAL ARTERIAL DISEASE OUTCOMESR01HL064739 · NHLBI · NORTHWESTERN UNIVERSITY · PI MCDERMOTT, MARY MCGRAE · 2001 to 2004
$2.1M
NHLBI NIH HHS R01 HL064739NHLBI NIH HHS R01 HL071223NHLBI NIH HHS R01 HL076298NHLBI NIH HHS R01 HL083064NHLBI NIH HHS R01 HL089619NHLBI NIH HHS R01 HL109244
6 · The paper itself

Abstract

objectiveThe objective of this study was to determine whether blacks with lower extremity peripheral artery disease (PAD) have faster functional decline than whites with PAD.

methodsParticipants with ankle-brachial index <0.90 were identified from Chicago medical centers and observed longitudinally. Mobility impairment and the 6-minute walk were assessed at baseline and every 6 to 12 months. Mobility loss was defined as becoming unable to walk up and down a flight of stairs or to walk ¼ mile without assistance.

resultsOf 1162 PAD participants, 305 (26%) were black. Median follow-up was 46.0 months. Among 711 PAD participants who walked 6 minutes continuously at baseline, black participants were more likely to become unable to walk 6 minutes continuously during follow-up (64/171 [37.4%] vs 156/540 [28.9%]; log-rank, P = .006). Black race was associated with becoming unable to walk 6 minutes continuously, adjusting for age, sex, ankle-brachial index, comorbidities, and other confounders (hazard ratio, 1.45; 95% confidence interval, 1.05-1.99; P = .022). This association was attenuated after adjustment for income and education (P = .229). Among 844 participants without baseline mobility impairment, black participants had a higher rate of mobility loss (64/209 [30.6%] vs 164/635 [25.8%]; log-rank, P = .009). Black race was associated with increased mobility loss, adjusting for potential confounders (hazard ratio, 1.42; 95% confidence interval, 1.04-1.94; P = .028). This association was attenuated after additional adjustment for income and education (P = .392) and physical activity (P = .113). There were no racial differences in average annual declines in 6-minute walk, usual-paced 4-meter walking velocity, or fast-paced 4-meter walking velocity.

conclusionsBlack PAD patients have higher rates of mobility loss and becoming unable to walk for 6 minutes continuously. These differences appear related to racial differences in socioeconomic status and physical activity.

Indexed as

Black or African AmericanEducational StatusHealth Status DisparitiesSocioeconomic FactorsWhite PeopleAgedAged, 80 and overAnkle Brachial IndexChicagoDependent AmbulationDisease ProgressionExercise ToleranceFemaleHumansLongitudinal StudiesLower Extremity

Identifiers

PMID28502539
PMCPMC5621652
OpenAlexW2613480717

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.