Evidence map›Paper›PMID 28502479›Full record

ArticleThe American journal of pathology2017

Megakaryocytes in Myeloproliferative Neoplasms Have Unique Somatic Mutations.

Belinda B Guo, Richard J Allcock, Bob Mirzai, Jacques A Malherbe, Fizzah A Choudry, Mattia Frontini, Hun Chuah, James Liang, Simon E Kavanagh, Rebecca Howman and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Variants of HCMVInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. The Role of Megakaryocytes in Myelofibrosis.Hematology/oncology clinics of North America · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Belinda B GuoSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.
Richard J AllcockSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; PathWest Laboratory Medicine, Nedlands, Western Australia, Australia.
Bob MirzaiSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; PathWest Laboratory Medicine, Nedlands, Western Australia, Australia.
Jacques A MalherbeSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.
Fizzah A ChoudryDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Mattia FrontiniDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom; British Heart Foundation Centre of Excellence, University of Cambridge, Cambridge, United Kingdom.
Hun ChuahDepartment of Health Western Australia, Royal Perth Hospital, Perth, Western Australia, Australia.
James LiangSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; Department of Health, Western Australia, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Simon E KavanaghSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; Department of Health, Western Australia, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Rebecca HowmanSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; PathWest Laboratory Medicine, Nedlands, Western Australia, Australia.
Willem H OuwehandDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom; British Heart Foundation Centre of Excellence, University of Cambridge, Cambridge, United Kingdom; Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Kathryn A FullerSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; PathWest Laboratory Medicine, Nedlands, Western Australia, Australia.
Wendy N ErberSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; PathWest Laboratory Medicine, Nedlands, Western Australia, Australia. Electronic address: wendy.erber@uwa.edu.au.
University of Western Australia · AUPathwest Laboratory Medicine · AUGovernment of Western Australia Department of Health · AUNational Health Service · GBSir Charles Gairdner Hospital · AUUniversity of Cambridge · GBWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloproliferative neoplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with hyperproliferation of myeloid cells. They are driven by mutations in the hemopoietic stem cell, most notably JAK2

Indexed as

AllelesBone MarrowBone Marrow NeoplasmsGene FrequencyGenomicsHigh-Throughput Nucleotide SequencingHumansJanus Kinase 2Leukemia, Myeloid, AcuteMegakaryocytesMutationMyeloid CellsMyeloproliferative DisordersPrimary MyelofibrosisReceptors, ThrombopoietinSequence Analysis, DNAJAK2 protein, humanJanus Kinase 2MPL protein, humanReceptors, Thrombopoietin

Identifiers

PMID28502479
PMCPMC5500825
OpenAlexW2612541250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.