Evidence map›Paper›PMID 28502443›Full record

ReviewPediatric clinics of North America2017

Hepatitis B and C.

Wikrom Karnsakul, Kathleen B Schwarz

Abstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Blood-borne viral infections in pediatric hemodialysis.Pediatric nephrology (Berlin, Germany) · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Wikrom KarnsakulPediatric Liver Center, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 2-117, Baltimore, MD 21287, USA. Electronic address: wkarnsa1@jhmi.edu.
Kathleen B SchwarzPediatric Liver Center, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 2-116, Baltimore, MD 21287, USA.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Immunologic and Virologic Correlates of the Age-Related Decrease in HBV DNA in ChildrenU01DK082916 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MURRAY, KAREN F, RODRIGUEZ BAEZ, NORBERTO · 2008 to 2019
$5.0M
NIDDK NIH HHS U01 DK082916
6 · The paper itself

Abstract

Chronic viral hepatitis is a global health threat and financial burden. Hepatitis B and C viruses (HBV and HCV) are the most common causes of chronic viral hepatitis in the United States. Most cases are asymptomatic before adulthood. Research has resulted in effective therapy for HCV and the promise of effective therapies for HBV. For HCV, therapy is pegylated interferon and ribavirin. Clinical trials with effective direct-acting antiviral agents are underway in pediatrics. For HBV, approved agents are alpha-interferon, lamivudine, adefovir, tenofovir, and entecavir. However, treatment seldom results in functional cure and more effective therapies are urgently needed.

Indexed as

AdolescentAdultAntiviral AgentsChildChild, PreschoolFemaleHepatitis BHepatitis CHepatitis VirusesHumansMaleAntiviral AgentsDirect-acting antiviral agentsHepatitis BHepatitis CPegylated interferonSpontaneous viral clearanceSustained virologic response

Identifiers

PMID28502443
PMCPMC5433262
OpenAlexW2614019887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.