Evidence map›Paper›PMID 28502091›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2017

Increased Pretransplant Frequency of CD28

M Cortes-Cerisuelo, S J Laurie, D V Mathews, P D Winterberg, C P Larsen, A B Adams, M L Ford

Open access · bronzeAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 62 citations in OpenAlex.

  1. Trial
  2. Challenges of calcineurin inhibitor withdrawal following combined pancreas and kidney transplantation: Results of a prospective, randomized clinical trial.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Trial
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Biopsy-Proven T-Cell Mediated Rejection After Belatacept Rescue Conversion: A Multicenter Retrospective Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. TIGIT agonism alleviates costimulation blockade-resistant rejection in a regulatory T cell-dependent manner.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. TIGIT regulates apoptosis of risky memory T cell subsets implicated in belatacept-resistant rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  19. Kidney transplantation in highly sensitized recipients.Kidney research and clinical practice · 2021
    Article
  20. Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

M Cortes-CerisueloEmory Transplant Center, Atlanta, GA.
S J LaurieEmory Transplant Center, Atlanta, GA.
D V MathewsEmory Transplant Center, Atlanta, GA.
P D WinterbergEmory Transplant Center, Atlanta, GA.
C P LarsenEmory Transplant Center, Atlanta, GA.
A B AdamsEmory Transplant Center, Atlanta, GA.
M L FordEmory Transplant Center, Atlanta, GA.
Emory Healthcare · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Determinants of T Cell Fate in Transplantation ToleranceR01AI073707 · NIAID · EMORY UNIVERSITY · PI FORD, MANDY L · 2008 to 2021
$4.0M
Costimulatory and Coinhibitory Receptor Control of Alloreactive T Cell ResponsesR01AI104699 · NIAID · EMORY UNIVERSITY · PI FORD, MANDY L · 2013 to 2017
$2.1M
Role of T cells in Uremic CardiomyopathyK08DK111998 · NIDDK · EMORY UNIVERSITY · PI WINTERBERG, PAMELA D · 2017 to 2022
$810k
The Role of 2B4 Coinhibition in Transplantation and ImmunityF31AI114250 · NIAID · EMORY UNIVERSITY · PI LAURIE, SONIA JESSICA · 2014 to 2017
$173k
Novel Combined Costimulation and CD122 Blockade in Islet TransplantationF30DK109665 · NIDDK · EMORY UNIVERSITY · PI MATHEWS, DAVID · 2016 to 2018
$146k
NIAID NIH HHS F31 AI114250NIAID NIH HHS R01 AI073707NIAID NIH HHS R01 AI104699NIDDK NIH HHS F30 DK109665NIDDK NIH HHS K08 DK111998NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

While most human T cells express the CD28 costimulatory molecule constitutively, it is well known that age, inflammation, and viral infection can drive the generation of CD28

Indexed as

AbataceptAdultAgedCase-Control StudiesCD28 AntigensCD8-Positive T-LymphocytesDrug ResistanceFemaleFollow-Up StudiesGlomerular Filtration RateGraft RejectionGraft SurvivalHumansImmunologic MemoryImmunosuppressive AgentsKidney Failure, ChronicAbataceptCD28 AntigensImmunosuppressive Agentsbasic (laboratory) research/sciencebiomarkercostimulationfusion proteins and monoclonal antibodies: belataceptimmune regulationimmunobiologyimmunosuppressantimmunosuppression/immune modulationkidney transplantation/nephrologyT cell biology

Identifiers

PMID28502091
PMCPMC5599135
OpenAlexW2613714577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.