Evidence map›Paper›PMID 28502089›Full record

ArticleImmunology2017

Association between cytokine profile and transcription factors produced by T-cell subsets in early- and late-onset pre-eclampsia.

Vanessa R Ribeiro, Mariana Romao-Veiga, Graziela G Romagnoli, Mariana L Matias, Priscila R Nunes, Vera Therezinha M Borges, Jose C Peracoli, Maria Terezinha S Peracoli

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Importance of STAT3 signaling in preeclampsia (Review).International journal of molecular medicine · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Plasma cell-free extrachromosomal circular DNA is a molecular hallmark of preeclampsia.Computational and structural biotechnology journal · 2025
    Article
  15. A Narrative Review on the Pathophysiology of Preeclampsia.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. VASCULAR AND RENAL MECHANISMS OF PREECLAMPSIA.Current opinion in physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Vanessa R RibeiroDepartment of Gynaecology and Obstetrics, Medical School, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.
Mariana Romao-VeigaDepartment of Microbiology and Immunology, Institute of Biosciences, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.ORCID 0000-0002-8990-0237
Graziela G RomagnoliDepartment of Microbiology and Immunology, Institute of Biosciences, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.
Mariana L MatiasDepartment of Gynaecology and Obstetrics, Medical School, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.
Priscila R NunesDepartment of Gynaecology and Obstetrics, Medical School, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.
Vera Therezinha M BorgesDepartment of Gynaecology and Obstetrics, Medical School, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.
Jose C PeracoliDepartment of Gynaecology and Obstetrics, Medical School, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.
Maria Terezinha S PeracoliDepartment of Microbiology and Immunology, Institute of Biosciences, Botucatu Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.ORCID 0000-0002-0936-9512
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pre-eclampsia (PE) is an obstetric pathology characterized by abnormal activation of the innate and adaptive immune systems dependent on the imbalance of T helper subsets. The present study aimed to evaluate the gene and protein expression of T helper type 1 (Th1)/Th2/Th17/regulatory T (Treg) cell transcription factors in peripheral blood lymphocytes from pregnant women with PE employing quantitative RT-PCR and flow cytometry techniques, as well as the cytokine profile produced by these CD4

Indexed as

Adaptive ImmunityAdolescentAdultBiomarkersCase-Control StudiesCytokinesFemaleForkhead Transcription FactorsGATA3 Transcription FactorGene Expression RegulationHumansInflammation MediatorsNuclear Receptor Subfamily 1, Group F, Member 3PhenotypePre-EclampsiaPregnancyBiomarkersCytokinesForkhead Transcription FactorsFOXP3 protein, humanGATA3 protein, humanGATA3 Transcription FactorInflammation MediatorsNuclear Receptor Subfamily 1, Group F, Member 3RNA, MessengerRORC protein, humanTranscription Factorscytokinesregulatory T cellsreproductive immunologyT cellstranscription factors

Identifiers

PMID28502089
PMCPMC5543493
OpenAlexW2613900373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.