Trial reportThe journal of pain2017
Responsiveness and Minimally Important Differences for 4 Patient-Reported Outcomes Measurement Information System Short Forms: Physical Function, Pain Interference, Depression, and Anxiety in Knee Osteoarthritis.
Trial report in The journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 106 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of a Smartphone Wellness App to Improve Mental Well-being: A Pilot Study
Optimizing Implementation of Mental Health Intervention Within Orthopedic Care
Who cites it
106 citing papers in PubMed, 4 syntheses or guidelines pooled it, 199 citations in OpenAlex.
- Pearls and pitfalls of PROMIS clinically significant outcomes in orthopaedic surgery.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Pooled it
- Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Pooled it
- Brief communication: use of the minimal important difference for a meta-analysis on exercise and anxiety in adults with arthritis.Clinical rheumatology · 2018Pooled it
- Randomized comparative effectiveness study of 1-session vs 8-session online behavioral treatment for chronic pain: protocol for the national PROGRESS study.Pain medicine (Malden, Mass.) · 2026Trial
- Bright IDEAS-YA Skills Training and Psychosocial Outcomes of Young Adults With Cancer: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Online 1-session Empowered Relief in Marfan syndrome and related diseases: a single-arm feasibility and pilot efficacy study.Scientific reports · 2026Trial
- Implementation of Group Physical Therapy for Knee Osteoarthritis: A Cluster Randomized Clinical Trial.JAMA network open · 2025Trial
- Can We Borrow Your Intervention? Randomized Controlled Trial of an Older Adult Telehealth Wellness Promotion Program Adapted for Middle-Aged Adults With Physical Disability.The Gerontologist · 2025Trial
- Early Functional Outcomes in Low Back Pain Subjects with a Novel Interspinous Fusion Device: REFINE Study 6-Month Results.Journal of pain research · 2023Trial
- An app-based just-in-time-adaptive self-management intervention for care partners: The CareQOL feasibility pilot study.Rehabilitation psychology · 2022Trial
- Trial
- Web-Based Mindfulness-Based Interventions for Well-being: Randomized Comparative Effectiveness Trial.Journal of medical Internet research · 2022Trial
- Health-Related Quality of Life Among United States Service Members with Low Back Pain Receiving Usual Care Plus Chiropractic Care vs Usual Care Alone: Secondary Outcomes of a Pragmatic Clinical Trial.Pain medicine (Malden, Mass.) · 2022Trial
- A Psycholgical Intervention Delivered by Automated Mobile Phone Messaging Stabilized Hip and Knee Function During the COVID-19 Pandemic: A Randomized Controlled Trial.The Journal of arthroplasty · 2022Trial
- Videoconference Intervention for Distance Caregivers of Patients With Cancer: A Randomized Controlled Trial.JCO oncology practice · 2021Trial
- The Effect of the "Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2020Trial
- Effect of Electroacupuncture vs Sham Treatment on Change in Pain Severity Among Adults With Chronic Low Back Pain: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Individual vs. Group Delivery of Acupuncture Therapy for Chronic Musculoskeletal Pain in Urban Primary Care-a Randomized Trial.Journal of general internal medicine · 2020Trial
- A pragmatic clinical trial examining the impact of a resilience program on college student mental health.Depression and anxiety · 2020Trial
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Patient-Reported Outcomes Measurement Information System (PROMIS) instruments can provide valid, interpretable measures of health status among adults with osteoarthritis (OA). However, their ability to detect meaningful change over time is unknown. We evaluated the responsiveness and minimally important differences (MIDs) for 4 PROMIS Short Forms: Physical Function, Pain Interference, Depression, and Anxiety. We analyzed adults with symptomatic knee OA from our randomized trial comparing Tai Chi and physical therapy. Using baseline and 12-week scores, responsiveness was evaluated according to consensus standards by testing 6 a priori hypotheses of the correlations between PROMIS and legacy change scores. Responsiveness was considered high if ≥5 hypotheses were confirmed, and moderate if 3 or 4 were confirmed. MIDs were evaluated according to prospective change for people achieving previously-established MID on legacy comparators. The lowest and highest MIDs meeting a priori quality criteria formed a MID range for each PROMIS Short Form. Among 165 predominantly female (70%) and white (57%) participants, mean age was 61 years and body mass index was 33. PROMIS Physical Function had 5 confirmed hypotheses and Pain Interference, Depression, and Anxiety had 3 or 4. MID ranges were: Depression = 3.0 to 3.1; Anxiety = 2.3 to 3.4; Physical Function = 1.9 to 2.2; and Pain Interference = 2.35 to 2.4. PROMIS Physical Function has high responsiveness, and Depression, Anxiety, and Pain Interference have moderate responsiveness among adults with knee OA. We established the first MIDs for PROMIS in this population, and provided an important standard of reference to better apply or interpret PROMIS in future trials or clinical practice. PERSPECTIVE: This study examined whether PROMIS Short Form instruments (Physical Function, Pain Interference, Depression, and Anxiety) were able to detect change over time among adults with knee OA, and provided minimally important change estimates for each measure. This standard of reference can help apply or interpret these instruments in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.