ArticleJournal of controlled release : official journal of the Controlled Release Society2017
Treg-recruiting microspheres prevent inflammation in a murine model of dry eye disease.
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In one paragraph
Article in Journal of controlled release : official journal of the Controlled Release Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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0cells of the map it votes in
41citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
What it found
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Who cites it
41 citing papers in PubMed, 58 citations in OpenAlex.
- Self-Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Regulatory T cell attracting therapy accelerates skeletal muscle functional recovery following injury.Scientific reports · 2026Article
- IL-2: a promising topical treatment for Sjögren's disease-related dry eye disease.Arthritis research & therapy · 2026Article
- UCMSC-derived exosomes ameliorate dry eye disease pathogenesis by modulating neutrophils on Th17/Treg balance.Scientific reports · 2026Article
- The Immunobiology of Dry Eye Disease: A Review of the Pathogenesis, Regulation and Therapeutic Implications.International journal of molecular sciences · 2025Review
- Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro-Inflammatory Macrophage Activation.Advanced healthcare materials · 2025Article
- Characterization of T cells in the progression of dry eye disease using single-cell RNA sequencing in mice.European journal of medical research · 2025Article
- ROS-Responsive Microneedle Patches Enable Peri-Lacrimal Gland Therapeutic Administration for Long-Acting Therapy of Sjögren's Syndrome-Related Dry Eye.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Activation of α2B/2C adrenergic receptor ameliorates ocular surface inflammation through enhancing regulatory T cell function.Mucosal immunology · 2025Article
- Single-Nuclei Characterization of Lacrimal Gland in Scopolamine-Induced Dry Eye Disease.Investigative ophthalmology & visual science · 2024Article
- Identification of HDAC9 and ARRDC4 as potential biomarkers and targets for treatment of type 2 diabetes.Scientific reports · 2024Article
- Recommendations for nutritional supplements for dry eye disease: current advances.Frontiers in pharmacology · 2024Review
- Employing Feature Selection Algorithms to Determine the Immune State of Mice Model of Rheumatoid Arthritis.IEEE journal of biomedical and health informatics · 2023Article
- Ocular Surface Allostasis-When Homeostasis Is Lost: Challenging Coping Potential, Stress Tolerance, and Resilience.Biomolecules · 2023Review
- Immune response differences in degradable and non-degradable alloy implants.Bioactive materials · 2023Review
- Ocular surface immune cell diversity in dry eye disease.Indian journal of ophthalmology · 2023Review
- Biomaterial mediated simultaneous delivery of spermine and alpha ketoglutarate modulate metabolism and innate immune cell phenotype in sepsis mouse models.Biomaterials · 2023Article
- Mass cytometry reveals the corneal immune cell changes at single cell level in diabetic mice.Frontiers in endocrinology · 2023Article
- Engineering Advanced Drug Delivery Systems for Dry Eye: A Review.Bioengineering (Basel, Switzerland) · 2022Review
- Short term, low dose alpha-ketoglutarate based polymeric nanoparticles with methotrexate reverse rheumatoid arthritis symptoms in mice and modulate T helper cell responses.Biomaterials science · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Michelle L RatayDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States.
Andrew J GlowackiDepartment of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA 15216, United States.
Stephen C BalmertDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States.
Abhinav P AcharyaDepartment of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA 15216, United States.
Julia PolatDepartment of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States.
Lawrence P AndrewsDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, United States.
Morgan V FedorchakDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States.
Joel S SchumanDepartment of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States.
Dario A A VignaliDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, United States; Department of Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, United States.
Steven R LittleDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States; Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA 15216, United States; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, United States. Electronic address: srlittle@pitt.edu.
University of Pittsburgh · USUPMC Hillman Cancer Center · US
Funding
Synergies among inhibitory receptors in tolerance, cancer & antiviral immunityP01AI108545 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Dario AA Vignali · 2015 to 2026
$30.8MVirus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8MNRSA Training CoreTL1TR001858 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RADOMSKI, THOMAS, RUBIO, DORIS M · 2016 to 2025
$11.1MParameters that Underlie Treg Insufficiency in Autoimmune DiabetesR01DK089125 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VIGNALI, DARIO AA · 2011 to 2020
$2.9MUniversity of Pittsburgh Clinical and Translational Science InstituteTL1TR000145 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$872kNCATS NIH HHS TL1 TR000145NCATS NIH HHS TL1 TR001858NEI NIH HHS P30 EY008098NIAID NIH HHS P01 AI108545NIDDK NIH HHS R01 DK089125
Abstract
Dry eye disease (DED) is a common ocular disorder affecting millions of individuals worldwide. The pathology of DED involves the infiltration of CD4
Indexed as
AnimalsAnti-Inflammatory AgentsChemokine CCL22Delayed-Action PreparationsDisease Models, AnimalDrug Delivery SystemsDry Eye SyndromesFemaleInflammationMice, Inbred BALB CT-Lymphocytes, RegulatoryAnti-Inflammatory AgentsChemokine CCL22Delayed-Action PreparationsCCL22Drug deliveryDry eye diseaseTreg-recruiting microspheresTregs
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.