Evidence map›Paper›PMID 28501646›Full record

ArticleJournal of biomedical informatics2017

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop.

Kathleen M Jagodnik, Simon Koplev, Sherry L Jenkins, Lucila Ohno-Machado, Benedict Paten, Stephan C Schurer, Michel Dumontier, Ruben Verborgh, Alex Bui, Peipei Ping and 4 more

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kathleen M JagodnikDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1215, New York, NY 10029, USA.
Simon KoplevDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1215, New York, NY 10029, USA.
Sherry L JenkinsDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1215, New York, NY 10029, USA.
Lucila Ohno-MachadoHealth System Department of Biomedical Informatics, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92083, USA; Health Services Research, San Diego Veterans Administration Health System, San Diego, CA 92083, USA.
Benedict PatenUC Santa Cruz Genomics Institute, University of California, Santa Cruz, 1156 High St., Santa Cruz, CA 95060, USA.
Stephan C SchurerDepartment of Molecular and Cellular Pharmacology, University of Miami, 331461120 NW 14th Street, CRB 650 (M-857), Miami, FL 33136, USA.
Michel DumontierInstitute for Data Science, Universiteit Maastricht, Minderbroedersberg 4-6, 6211 LK Maastricht, Netherlands.
Ruben VerborghGhent University - iMinds Research Foundation Flanders, St. Pietersnieuwstraat 33, 9000 Gent, Belgium.
Alex BuiDepartment of Radiological Sciences, UCLA School of Medicine, Los Angeles, CA 90095, USA; Department of Bioengineering, UCLA Henri Samueli School of Engineering, Los Angeles, CA 90095, USA.
Peipei PingDepartments of Physiology, Medicine, and Bioinformatics, UCLA School of Medicine, Los Angeles, CA 90095, USA.
Neil J McKennaDepartment of Molecular and Cellular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
Ravi MadduriDepartment of Mathematics and Computer Science, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439, USA.
Ajay PillaiDivision of Genome Sciences, National Human Genome Research Institute, National Institutes of Health, 31 Center Drive, MSC 2152, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Avi Ma'ayanDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1215, New York, NY 10029, USA. Electronic address: avi.maayan@mssm.edu.

Funding

Data Coordination and Integration Center for LINCS-BD2KU54HL127624 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MA'AYAN, AVI, SCHURER, STEPHAN C · 2014 to 2019
$23.5M
Training SubprojectU54HG007990 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, PATTERSON, DAVID · 2014 to 2018
$14.8M
TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Hardening Globus Genomics to make large-scale genomics analysis available for everybodyR01HG009018 · NHGRI · UNIVERSITY OF CHICAGO · PI FOSTER, IAN, MADDURI, RAVI KIRAN · 2016 to 2019
$1.6M
NHGRI NIH HHS R01 HG009018NHGRI NIH HHS U54 HG007990NHLBI NIH HHS T32 HL007824NHLBI NIH HHS U54 HL127624
6 · The paper itself

Abstract

The volume and diversity of data in biomedical research have been rapidly increasing in recent years. While such data hold significant promise for accelerating discovery, their use entails many challenges including: the need for adequate computational infrastructure, secure processes for data sharing and access, tools that allow researchers to find and integrate diverse datasets, and standardized methods of analysis. These are just some elements of a complex ecosystem that needs to be built to support the rapid accumulation of these data. The NIH Big Data to Knowledge (BD2K) initiative aims to facilitate digitally enabled biomedical research. Within the BD2K framework, the Commons initiative is intended to establish a virtual environment that will facilitate the use, interoperability, and discoverability of shared digital objects used for research. The BD2K Commons Framework Pilots Working Group (CFPWG) was established to clarify goals and work on pilot projects that address existing gaps toward realizing the vision of the BD2K Commons. This report reviews highlights from a two-day meeting involving the BD2K CFPWG to provide insights on trends and considerations in advancing Big Data science for biomedical research in the United States.

Indexed as

Datasets as TopicInformation DisseminationNational Institutes of Health (U.S.)Biomedical ResearchHumansKnowledgeTranslational Research, BiomedicalUnited StatesAccessibilityBig DataFAIR principlesFindabilityInteroperabilityReusability

Identifiers

PMID28501646
PMCPMC5545976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.