Evidence map›Paper›PMID 28501635›Full record

ArticleJournal of theoretical biology2017

Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms.

Jie Zhang, Angela G Fleischman, Dominik Wodarz, Natalia L Komarova

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of theoretical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jie ZhangDepartment of Mathematics, USA.
Angela G FleischmanDivision of Hematology/Oncology, USA.
Dominik WodarzDepartment of Ecology and Evolutionary Biology, University of California Irvine, Irvine, CA 92697, USA; Department of Mathematics, USA.
Natalia L KomarovaDepartment of Mathematics, USA; Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, CA 92697, USA. Electronic address: komarova@uci.edu.
University of California, Irvine · US

Funding

Aspirin and Cancer Prevention in Lynch Syndrome: From Cell to Population DataU01CA187956 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI GOEL, AJAY, WODARZ, DOMINIK F · 2014 to 2018
$2.7M
NCI NIH HHS U01 CA187956
6 · The paper itself

Abstract

Myeloproliferative neoplasm (MPN) is a hematologic malignancy characterized by the clonal outgrowth of hematopoietic cells with a somatically acquired mutation most commonly in JAK2 (JAK2

Indexed as

MutationCell DifferentiationCell DivisionCell Transformation, NeoplasticHematologic NeoplasmsHematopoietic Stem CellsHumansInflammationJanus Kinase 2Models, BiologicalMyeloproliferative DisordersNeoplasm ProteinsJAK2 protein, humanJanus Kinase 2Neoplasm ProteinsAxiomatic modelingEvolutionary dynamicsHematopoietic diseaseODE modeling

Identifiers

PMID28501635
PMCPMC5689470
OpenAlexW2951039728

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.