Evidence map›Paper›PMID 28501331›Full record

ArticleToxicology and applied pharmacology2017

The expression of keratin 6 is regulated by the activation of the ERK1/2 pathway in arsenite transformed human urothelial cells.

Andrea Slusser-Nore, Scott H Garrett, Xu Dong Zhou, Donald A Sens, Mary Ann Sens, Seema Somji

Open access · greenAbstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Epidermal growth factor receptor function in the human urothelium.International urology and nephrology · 2018
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrea Slusser-NoreDepartment of Pathology, University of North Dakota, School of Medicine and Health Sciences, 1301 N. Columbia Road, Stop 9037, Grand Forks, ND 58202, United States. Electronic address: andrea.slusser@und.edu.
Scott H GarrettDepartment of Pathology, University of North Dakota, School of Medicine and Health Sciences, 1301 N. Columbia Road, Stop 9037, Grand Forks, ND 58202, United States. Electronic address: scott.garrett@med.und.edu.
Xu Dong ZhouDepartment of Pathology, University of North Dakota, School of Medicine and Health Sciences, 1301 N. Columbia Road, Stop 9037, Grand Forks, ND 58202, United States. Electronic address: xudong.zhou@med.und.edu.
Donald A SensDepartment of Pathology, University of North Dakota, School of Medicine and Health Sciences, 1301 N. Columbia Road, Stop 9037, Grand Forks, ND 58202, United States. Electronic address: donald.sens@med.und.edu.
Mary Ann SensDepartment of Pathology, University of North Dakota, School of Medicine and Health Sciences, 1301 N. Columbia Road, Stop 9037, Grand Forks, ND 58202, United States. Electronic address: mary.sens@med.und.edu.
Seema SomjiDepartment of Pathology, University of North Dakota, School of Medicine and Health Sciences, 1301 N. Columbia Road, Stop 9037, Grand Forks, ND 58202, United States. Electronic address: seema.somji@med.und.edu.
University of North Dakota · US

Funding

Research CoresP20GM103442 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI Chris Jurgens · 2012 to 2026
$53.0M
NIGMS NIH HHS P20 GM103442
6 · The paper itself

Abstract

Urothelial cancers have an environmental etiological component, and previous studies from our laboratory have shown that arsenite (As

Indexed as

AnimalsArsenitesCell Line, TransformedCell Line, TumorEnzyme ActivationGene Expression Regulation, NeoplasticHumansKeratin-6MAP Kinase Signaling SystemMiceMice, NudeUrinary Bladder NeoplasmsUrotheliumXenograft Model Antitumor AssaysarseniteArsenitesKeratin-6ArseniteBiomarkerBladder cancerKeratin 6MAPKUROtsa

Identifiers

PMID28501331
PMCPMC5649386
OpenAlexW2612212605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.