Evidence map›Paper›PMID 28500982›Full record

ArticleJournal of affective disorders2017

Abnormal sleep duration associated with hastened depressive recurrence in bipolar disorder.

Anda Gershon, Dennis Do, Satyanand Satyanarayana, Saloni Shah, Laura D Yuen, Farnaz Hooshmand, Shefali Miller, Po W Wang, Terence A Ketter

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

  1. A randomized controlled study of weighted chain blankets for insomnia in psychiatric disorders.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Bipolar Disorder, Circadian Rhythm and Clock Genes.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Review
  8. Article
  9. Switching to lemborexant for the management of insomnia in mental disorders: the SLIM study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  10. Factors Associated With Sleep Disturbance Amongst Youth With Bipolar Disorder.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2022
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anda GershonDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Dennis DoDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Satyanand SatyanarayanaDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Saloni ShahDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Laura D YuenDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Farnaz HooshmandDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Shefali MillerDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Po W WangDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States.
Terence A KetterDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States. Electronic address: tketter@stanford.edu.
Stanford University · US

Funding

Sleep and Circadian Dysregulation in Pediatric Bipolar DisorderK01MH100433 · NIMH · STANFORD UNIVERSITY · PI GERSHON, ANDA · 2014 to 2017
$723k
NIMH NIH HHS K01 MH100433
6 · The paper itself

Abstract

backgroundAbnormal sleep duration (ASD, <6 or ≥9h) is common in bipolar disorder (BD), and often persists beyond acute mood episodes. Few longitudinal studies have examined the ASD's impact upon BD illness course. The current study examined the longitudinal impact of ASD upon bipolar depressive recurrence/recovery.

methodsOutpatients referred to the Stanford BD Clinic during 2000-2011 were assessed with the Systematic Treatment Enhancement Program for BD (STEP-BD) Affective Disorders Evaluation at baseline, and with the Clinical Monitoring Form at monthly follow-ups for up to two years of naturalistic treatment. Prevalence and clinical correlates of ASD in 93 recovered (euthymic ≥8 weeks) and 153 depressed BD patients were assessed. Kaplan-Meier analyses (Log-Rank tests) assessed relationships between baseline ASD and longitudinal depressive severity, with Cox Proportional Hazard analyses assessing potential mediators.

resultsASD was only half as common among recovered versus depressed BD outpatients, but was significantly associated with hastened depressive recurrence (Log-Rank p=0.007), mediated by lifetime anxiety disorder and attenuated by lifetime history of psychosis, and had only a non-significant tendency towards association with delayed depressive recovery (Log-Rank p=0.07). In both recovered and depressed BD outpatients, baseline ASD did not have significant association with any baseline BD illness characteristic. LIMITATIONS: Self-reported sleep duration. Limited generalizability beyond our predominately white, female, educated, insured American BD specialty clinic sample.

conclusionsBaseline ASD among recovered BD patients may be a risk marker for hastened depressive recurrence, suggesting it could be an important therapeutic target between mood episodes.

Indexed as

AdultAffectAnxiety DisordersBipolar DisorderDepressionFemaleFollow-Up StudiesHumansKaplan-Meier EstimateLongitudinal StudiesMaleMiddle AgedOutpatientsPrevalenceRecurrenceSleepBipolar depressionBipolar disorderRecurrenceSleep

Identifiers

PMID28500982
PMCPMC6389505
OpenAlexW2610594631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.