Evidence map›Paper›PMID 28500759›Full record

ArticleMedical physics2017

A Monte Carlo model for mean glandular dose evaluation in spot compression mammography.

Antonio Sarno, David R Dance, Ruben E van Engen, Kenneth C Young, Paolo Russo, Francesca Di Lillo, Giovanni Mettivier, Kristina Bliznakova, Baowei Fei, Ioannis Sechopoulos

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Antonio SarnoDipartimento di Fisica "Ettore Pancini", Università di Napoli Federico II, Via Cintia, I-80126, Napoli, Italy.
David R DanceNational Co-ordinating Centre for the Physics of Mammography (NCCPM), Royal Surrey County Hospital, Guildford, GU2 7XX, UK.
Ruben E van EngenDutch Reference Centre for Screening (LRCB), P.O. Box 6873, 6503 GJ, Nijmegen, The Netherlands.
Kenneth C YoungNational Co-ordinating Centre for the Physics of Mammography (NCCPM), Royal Surrey County Hospital, Guildford, GU2 7XX, UK.
Paolo RussoDipartimento di Fisica "Ettore Pancini", Università di Napoli Federico II, Via Cintia, I-80126, Napoli, Italy.
Francesca Di LilloDipartimento di Fisica "Ettore Pancini", Università di Napoli Federico II, Via Cintia, I-80126, Napoli, Italy.
Giovanni MettivierDipartimento di Fisica "Ettore Pancini", Università di Napoli Federico II, Via Cintia, I-80126, Napoli, Italy.
Kristina BliznakovaDepartment of Electronics, Technical University of Varna, 1 Studentska Str, Varna, 9010, Bulgaria.
Baowei FeiDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, 1701 Upper Gate Drive Northeast, Suite 5018, Atlanta, GA, 30322, USA.
Ioannis SechopoulosDutch Reference Centre for Screening (LRCB), P.O. Box 6873, 6503 GJ, Nijmegen, The Netherlands.
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli · ITRoyal Surrey County Hospital · GBDutch Expert Centre for Screening · NLEmory University · USRadboud University Nijmegen · NLTechnical University of Varna · BG

Funding

ACADEMIC-INDUSTRIAL PARTNERSHIP FOR TRANSLATION OF PET/TRUS GUIDED INTERVENTIONR01CA204254 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2017 to 2021
$2.0M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
Image Quality Improvement and Breast Compression Reduction in Breast TomosynthesiR01CA163746 · NCI · RADBOUD UNIVERSITY NIJMEGEN MED CTR · PI SECHOPOULOS, IOANNIS · 2012 to 2015
$1.2M
Image Quality Improvement and Performance Assessment of Dedicated Breast CTR01CA181171 · NCI · STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM I.O. · PI SECHOPOULOS, IOANNIS · 2015 to 2020
$1.1M
Targeted fusion biopsy using anti-[18F]FACBC PET/CT and real-time 3D ultrasound gR21CA176684 · NCI · EMORY UNIVERSITY · PI FEI, BAOWEI, MASTER, VIRAJ · 2013 to 2014
$568k
Cancer Research UK 17321NCI NIH HHS R01 CA156775NCI NIH HHS R01 CA163746NCI NIH HHS R01 CA181171NCI NIH HHS R01 CA204254NCI NIH HHS R21 CA176684
6 · The paper itself

Abstract

purposeTo characterize the dependence of normalized glandular dose (DgN) on various breast model and image acquisition parameters during spot compression mammography and other partial breast irradiation conditions, and evaluate alternative previously proposed dose-related metrics for this breast imaging modality.

methodsUsing Monte Carlo simulations with both simple homogeneous breast models and patient-specific breasts, three different dose-related metrics for spot compression mammography were compared: the standard DgN, the normalized glandular dose to only the directly irradiated portion of the breast (DgNv), and the DgN obtained by the product of the DgN for full field irradiation and the ratio of the mid-height area of the irradiated breast to the entire breast area (DgN

resultsThe DgN in spot compression mammography can vary considerably with breast area. However, the difference in breast thickness between the spot compressed area and the uncompressed area does not introduce a variation in DgN. As long as the spot compressed area is completely within the breast area and only the compressed breast portion is directly irradiated, its position and size does not introduce a variation in DgN for the homogeneous breast model. As expected, DgN is lower than DgNv for all partial breast irradiation areas, especially when considering spot compression areas within the clinically used range. DgN

conclusionAs part of the development of a new breast dosimetry model, a task undertaken by the American Association of Physicists in Medicine and the European Federation of Organizations of Medical Physics, these results provide insight on how DgN and two alternative dose metrics behave with various image acquisition and model parameters.

Indexed as

Computer SimulationMammographyRadiation DosageBreastBreast NeoplasmsFemaleHumansMonte Carlo MethodPressuremagnification mammographymammographymean glandular dosespot compression

Identifiers

PMID28500759
PMCPMC5534220
OpenAlexW2614009048

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.