Evidence map›Paper›PMID 28500756›Full record

ArticleeLife2017

Sphingomyelin metabolism controls the shape and function of the Golgi cisternae.

Felix Campelo, Josse van Galen, Gabriele Turacchio, Seetharaman Parashuraman, Michael M Kozlov, María F García-Parajo, Vivek Malhotra

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Dynamic Shape Modulation of Deflated and Adhered Lipid Vesicles.Journal of the American Chemical Society · 2025
    Article
  5. Regulation of yeast polarized exocytosis by phosphoinositide lipids.Cellular and molecular life sciences : CMLS · 2024
    Review
  6. Regulation of cellular and systemic sphingolipid homeostasis.Nature reviews. Molecular cell biology · 2024
    Review
  7. Article
  8. NKS1/ELMO4 is an integral protein of a pectin synthesis protein complex and maintains Golgi morphology and cell adhesion inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. SiScience · 2023
    Article
  12. Golgi-IP, a tool for multimodal analysis of Golgi molecular content.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Review
  14. Article
  15. Sending out molecules from the TGN.Current opinion in cell biology · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Felix CampeloICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0002-0786-9548
Josse van GalenCentre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Gabriele TuracchioInstitute of Protein Biochemistry, National Research Council of Italy, Naples, Italy.
Seetharaman ParashuramanInstitute of Protein Biochemistry, National Research Council of Italy, Naples, Italy.
Michael M KozlovDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
María F García-ParajoICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Vivek MalhotraCentre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0001-6198-7943
Institució Catalana de Recerca i Estudis Avançats · ESInstitute of Protein Biochemistry · ITInstitute of Photonic Sciences · ESTel Aviv University · ILUniversitat Pompeu Fabra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The flat Golgi cisterna is a highly conserved feature of eukaryotic cells, but how is this morphology achieved and is it related to its function in cargo sorting and export? A physical model of cisterna morphology led us to propose that sphingomyelin (SM) metabolism at the

Indexed as

Golgi ApparatusHeLa CellsHumansIntracellular MembranesSphingomyelinsSphingomyelinsbiophysicscell biologyGolgi complexhumanmembrane curvaturesphingomyelinstructural biology

Identifiers

PMID28500756
PMCPMC5462544
OpenAlexW2613379442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.